… BRAF mutation and DNA hypermethylation have linked sessile serrated adenomas/polyps
(SSA/Ps) to serrated colorectal … BRAF mutation and CIMP status of serrated polyps were not …

… 9 coined the term sessile serrated adenoma, which is now … or ZNRF3, 48 and DNA methylation
changes of the upstream … , BRAF mutation is a specific marker for a serrated pathway, …

… Finally, we investigated DNA methylation of cancer-associated … In the present study, TSAs
with BRAF mutation were … signaling differs among colorectal serrated polyps, depending on …

… The rate of BRAF mutation, an important gene mutation in the serrated-neoplasia pathway,
… DNA methylation, and structural rearrangements was beyond the scope of this study. …

… to predict the serrated derived colorectal cancer development. … Colorectal carcinogenesis
in serrated polyposis patients … Poor survival associated with the BRAF V600E mutation in …

… Braf mutation results in consistent DNA methylation changes analogous to CIMP in human
colorectal cancer.… . Serrated and non-serrated polyps of the colorectum: their prevalence in an …

… , serrated lesions seldom present APC mutations. The majority of CRCs arising from serrated
polyps tend to carry BRAF mutations, … low or high levels of DNA methylation [21]. CIMP-high …

… replaces sessile serrated adenoma and sessile serrated polyp. … There were no cases showing
MLH1 loss or BRAF mutation … -mutated, microsatellite-stable (MSS) colorectal carcinomas (…

… or only serrated polyps (Table S1). In the multivariate analysis, CIMP+ was associated with
… CIMP status to MACL development risk, we also examined polyps for mutations in the BRAF …

… adenoma carcinoma sequence, less evidence has been retrieved about serrated polyp-related …
markers categorizing CRC as exhibiting or not exhibiting DNA methylation based on …