Diabetes and Alzheimer's disease: might mitochondrial dysfunction help deciphering the common path?

MA Potenza, L Sgarra, V Desantis, C Nacci… - Antioxidants, 2021 - mdpi.com
… IAPP or amylin, a protein co-expressed and secreted with insulin … The IRS-1 inhibition
subsequent to TNF-α-mediated … cognition and brain plasticity long-term potentiation (LTP) in …

[HTML][HTML] Synaptic organizers in Alzheimer's disease: A classification based on amyloid-β sensitivity

AK Lee, H Khaled, N Chofflet… - Frontiers in Cellular …, 2020 - frontiersin.org
long-term potentiation (LTP), which is synaptic plasticity depending on postsynaptic N-Methyl-D-aspartate-type
glutamate receptor (NMDAR)-mediated … At the hippocampal CA1-…

Activity of selected group of monoterpenes in alzheimer's disease symptoms in experimental model studies—A non-systematic review

K Wojtunik-Kulesza, M Rudkowska… - International Journal of …, 2021 - mdpi.com
… and potentiation of the GABA A receptor-mediated response. … Additionally, hippocampal
long-term-potentiation was … High activity against Aβ aggregation along with explanation of …

… attenuates the cognitive deficits in a transgenic mouse model of Alzheimer's disease via modulating neuropathology and gut microbiota through suppressing C/EBPβ …

QQ Xu, ZR Su, W Yang, M Zhong, YF Xian… - Journal of …, 2023 - Springer
… /β were bilaterally injected into the hippocampal CA1 region in … microbiota disturbance-mediated
GI inflammation promotes … dysfunctions and abnormal long-term potentiation (LTP) are …

[PDF][PDF] Insulin Resistance and Diabetes Mellitus in Alzheimer's Disease. Cells 2021, 10, 1236

J Burillo, P Marqués, B Jiménez, C González-Blanco… - 2021 - academia.edu
through the modulation of insulin receptor clathrin-mediated … What is more important is that
amylin or hIAPP is cosecreted … long-term potentiation (LTP) and long-term depression (LTD). …

Establishing an In Vitro Model of Insulin Resistance in Human SH-SY5Y Cells and Investigating Its Impact on the Expression of BDNF and Its Receptors

M Nelson - 2023 - atrium.lib.uoguelph.ca
… -term and decreasing it with long-term treatments. proBDNF, … (PM) which occurs through
glycolysis-mediated increases in … diminished degradation and interaction with amylin, better …

Insulin in the brain: its pathophysiological implications for states related with central insulin resistance, type 2 diabetes and alzheimer's disease

E Blázquez Fernández, E Velázquez Sánchez… - 2024 - docta.ucm.es
through the blood–brain barrier using a receptor-mediated … that insulin protects against beta
amyloid-induced cell death. … called long-term potentiation (LTP) and long-term depression (…

Secondary metabolites from plants possessing inhibitory properties against beta-amyloid aggregation as revealed by thioflavin-T assay and correlations with …

R Stefanescu, GD Stanciu, A Luca, L Paduraru… - Biomolecules, 2020 - mdpi.com
… triggering receptor expressed on myeloid cells2 (Trem2) or Beta-… neuroprotection against
Aβ-mediated neurotoxicity by EGCG [… LTP, long-term potentiation; LTD, long-term depression of …

Role of Hydroxytyrosol and Oleuropein in the prevention of aging and related disorders: focus on neurodegeneration, skeletal muscle dysfunction and gut microbiota

L Micheli, L Bertini, A Bonato, N Villanova, C Caruso… - Nutrients, 2023 - mdpi.com
receptor α (PPAR α) that regulates cytochrome P450 and controls lipid homeostasis, the
activation of which mediates … also prevents deposition of amylin in these cells through its HTyr …

[HTML][HTML] Sialometabolism in brain health and Alzheimer's disease

P Rawal, L Zhao - Frontiers in Neuroscience, 2021 - frontiersin.org
mediates the attachment at C-2 carbon of sialic acid via one … regions along with less
synapses in the hippocampus and … Fas receptors are death receptors expressed on cell surfaces …