β-Arrestin–biased allosteric modulator potentiates carvedilol-stimulated β adrenergic receptor cardioprotection

J Wang, B Pani, I Gokhan, X Xiong, AW Kahsai… - Molecular …, 2021 - ASPET
… exercise-induced heart rate and the nonselective inhibition of both β 1 adrenergic receptor
(… effects in other tissues, such as bronchial and blood vessel constriction (Cleland et al., 2000)…

Pharmacologic treatments for acute respiratory distress syndrome

N Qadir, SY Chang - Critical care clinics, 2021 - criticalcare.theclinics.com
… tested, including those targeting ventilatorassociated lung injury (VALI), dead space ventilation,
inflammation, alveolar epithelial and capillary endothelial injury, and dysfunctional fluid …

Diacylglycerol Kinase is a Keystone Regulator of Signaling Relevant to the Pathophysiology of Asthma

MA Hernandez-Lara, J Richard… - … of Physiology-Lung …, 2024 - journals.physiology.org
… One group designed DGKγ-specific inhibitor and by radiolabeling and positron emission
536 tomography (PET) scans traced the molecule to cross the blood brain barrier and bind 537 …

Effect of twice daily inhaled albuterol on cardiopulmonary exercise outcomes, dynamic hyperinflation, and symptoms in secondhand tobacco-exposed persons with …

S Zeng, M Nishihama, L Weldemichael, H Lozier… - BMC Pulmonary …, 2024 - Springer
… In lungs, inhalation of albuterol and other β2-agonists are thought to mainly affect airway
smooth muscle cells and have a bronchodilatory effect, although effects on other lung cells (…

[PDF][PDF] Siyang Zeng1, 2, 3, Melissa Nishihama2, 3, Lemlem Weldemichael2, 3, Helen Lozier2, 3, 4, Warren M. Gold3 and

M Arjomandi - bmcpulmmed.biomedcentral.com
Beta2-adrenoceptor agonists as inhibitors of lung vascular permeability to radiolabelled
transferrin in the adult respiratory distress syndrome in man. Eur J Nucl Med. 1986;12(8):381–4. …

Pharmacological and genetic approaches to modulate energy metabolism in skeletal muscle cells

C Skagen - 2022 - duo.uio.no
… by a combination of functional studies using radiolabelled substrates with gene expression
… active activators and inhibitors. In paper I, the well-studied β2-AR agonist terbutaline was …

[HTML][HTML] Polyethylenimine (PEI) in gene therapy: Current status and clinical applications

J Casper, SH Schenk, E Parhizkar, P Detampel… - Journal of Controlled …, 2023 - Elsevier
… The potential of nucleic acid therapeutics is almost limitless, as it allows for a broad spectrum
of applications including inhibition of pathological protein production (ie, gene silencing), …

The effect of hypothalamic peptides, neurohormone C and proline-rich peptide-1on the Ca2+-handling system in heartin pathophysiological conditions

AG Guevorkian - Heliyon, 2020 - cell.com
Atthe Institute of Biochemistry named after H. Buniatyan we discovered and studied hypothalamic
peptides with coronary dilatory and antioxidant activities:neurohormone C (NC) and …

Preclinical Evaluation and Clinical Translation of Us-Pai for Assessment of Radiation-Induced Salivary Gland Injury

E Bolookat - 2021 - search.proquest.com
… salivary glands leads to increased vascular permeability, interstitial edema and perivascular
… It is a radiolabeled glucose analog, taken up by cells that rapidly consume and metabolize …

[图书][B] Functional insight on regulation of thermogenesis and creatine kinase B

CB Dykstra - 2021 - search.proquest.com
… in that showing radiolabelled adrenocorticotropic hormone … highly accurate assay using
radiolabelled β2-AR agonist 3[H]-… , we used an immunological inhibitor of colony stimulating …