[HTML][HTML] Striatal synaptic adaptations in Parkinson's disease

W Shen, S Zhai, DJ Surmeier - Neurobiology of disease, 2022 - Elsevier
… Similarly, levodopa therapy was originally aimed at re-balancing … does bidirectional plasticity
at glutamatergic synapses changesynaptic plasticity depend – either directly or indirectly – …

[HTML][HTML] Spike-timing-dependent plasticity mediated by dopamine and its role in Parkinson's disease pathophysiology

M Madadi Asl, AH Vahabie, A Valizadeh… - Frontiers in Network …, 2022 - frontiersin.org
… model for synaptic plasticity to modify synaptic connections … , structural plasticity and
homeostatic plasticity may change the … , this heterosynaptic plasticity is homeostatic which …

Concurrent thalamostriatal and corticostriatal spike-timing-dependent plasticity and heterosynaptic interactions shape striatal plasticity map

A Mendes, G Vignoud, S Perez, E Perrin… - Cerebral …, 2020 - academic.oup.com
… We found bidirectional Hebbian and anti-Hebbian spike-… ) were performed to assess
the change in synaptic efficacy. We … belonging to the direct (striatonigral) or indirect (striatopallido-…

[PDF][PDF] Striatum expresses region-specific plasticity consistent with distinct memory abilities

S Perez, Y Cui, G Vignoud, E Perrin, A Mendes… - Cell Reports, 2022 - cell.com
… , plasticity was engaged for all DMSMSNs and for striatonigral … to the striatonigral or
striatopallidal pathways (two-way ANOVA, … This more balanced response allows for a more …

Striatal circuit development and synapse maturation

RT Peixoto, Y Kozorovitskiy - Synapse Development and Maturation, 2020 - Elsevier
… SPNs establish early striatonigral connections prenatally, … The bidirectional regulation of
SPN structure and function in … What aspects of synaptogenesis and synaptic plasticity are …

[HTML][HTML] Selective activation of striatal indirect pathway suppresses levodopa induced-dyskinesias

I Castela, R Casado-Polanco, YVW Rubio… - Neurobiology of …, 2023 - Elsevier
… were analyzed using a two-way repeated measures ANOVA … a balance of activity between
the direct and indirect pathways… no change in dyskinesia after selectively inhibiting the direct

Astrocyte signaling gates long-term depression at corticostriatal synapses of the direct pathway

A Cavaccini, C Durkee, P Kofuji, R Tonini… - Journal of …, 2020 - Soc Neuroscience
… -astrocyte signaling contributes to synaptic plasticity in the DLS … Increasing evidence is
producing a fundamental shift in our … to the complexity of bidirectional astrocyte-neuron signaling, …

Symmetric and Asymmetric Synapses Driving Neurodegenerative Disorders

D Romaus-Sanjurjo, A Custodia, M Aramburu-Núñez… - Symmetry, 2021 - mdpi.com
… The balance between these two systems is critical to … changing, reflecting the high plasticity
presents in this network. The strength of these synapses can be modified in a bidirectional

[HTML][HTML] Neuro-immune cross-talk in the striatum: from basal ganglia physiology to circuit dysfunction

A Mancini, V Ghiglieri, L Parnetti, P Calabresi… - Frontiers in …, 2021 - frontiersin.org
… immune system is represented by the shift in an individual’s … to induce corticostriatal
bidirectional plasticity, with divergent … consecutive stimuli requires a balanced removal/reuptake of …

Dopaminergic input regulates the sensitivity of indirect pathway striatal spiny neurons to brain-derived neurotrophic factor

M Ayon-Olivas, D Wolf, T Andreska, N Granado… - Biology, 2023 - mdpi.com
… and altered synaptic plasticity at corticostriatal synapses. … gel; then, the voltage was
changed to 120 V once the samples … A balance between the activity of these two striatal output …