Critical aspects involved in lipid dispersion and digestion: emphasis on in vitro models and factors influencing lipolysis of oral lipid based formulations
… lipid excipient, surfactants, and co-solvents), the droplet size of … (LBFs) in enhancing drug
bioavailability. Static models … , DG, and MG-based LBFs of probucol. The results demonstrated …
bioavailability. Static models … , DG, and MG-based LBFs of probucol. The results demonstrated …
Recent approaches to investigate drug delivery systems through the lymphatic pathway using oral lipid-based formulations
SJ Jeong, WY Song, CW Park, DW Kim - Journal of Pharmaceutical …, 2024 - Springer
… absorption of medications is significantly influenced by the … IV lipid formulations are based
on water-soluble surfactants … of excipients for lipid-based formulations is influenced by several …
on water-soluble surfactants … of excipients for lipid-based formulations is influenced by several …
Lipid-based formulations to increase cannabidiol bioavailability: In vitro digestion tests, pre-clinical assessment and clinical trial
MAA De Prá, R Vardanega, CG Loss - International Journal of …, 2021 - Elsevier
… the lipid profile substantially influences CBD delivery and highlights the potential of the SEDDS
and GML formulations … In addition, the influence of surfactants and cosolvents can involve …
and GML formulations … In addition, the influence of surfactants and cosolvents can involve …
[HTML][HTML] Quality-by-design-based development of a voxelotor self-nanoemulsifying drug-delivery system with improved biopharmaceutical attributes
… the aqueous solubility and oral absorption of lipophilic drugs, … impact of excipients on the
performance of the formulation [10… effect of the surfactant and oil as absorption enhancers, and …
performance of the formulation [10… effect of the surfactant and oil as absorption enhancers, and …
Self-nanoemulsifying drug delivery systems with bioavailability potential
… fluid, and under the influence of gentle agitation … lipid bilayer, resulting in enhanced
permeability. Dissolution rate of drug is improved due to absorption-enhancing ability of surfactants. …
permeability. Dissolution rate of drug is improved due to absorption-enhancing ability of surfactants. …
[HTML][HTML] Self-nano-emulsifying drug-delivery systems: From the development to the current applications and challenges in oral drug delivery
… Surfactants and lipid components used in SNEDDSs can cooperate to enhance the GI …
selected due to its key influence in both formulation-loading capacity and drug absorption [14]. …
selected due to its key influence in both formulation-loading capacity and drug absorption [14]. …
Lymphatic Transport of Lipid-Based Drug Delivery System
… suitable lipids and surfactants are selected for the formulation of … Influence of bile on the
absorption of halofantrine from lipid-… Administration of lipid-based formulations to minipigs in the …
absorption of halofantrine from lipid-… Administration of lipid-based formulations to minipigs in the …
Self-nanoemulsifying systems for delivery of drugs
… Lipid phase and surfactant in SNEDDs can enhance the … The drug amount of has a great
influence on SNEDDs formulation, … the absorption site due to the lipid excipients contents in the …
influence on SNEDDs formulation, … the absorption site due to the lipid excipients contents in the …
[PDF][PDF] Self-nanoemulsifying drug delivery systems (SNEDDS): an advancement technology for oral drug delivery
B Morakul - Pharm Sci Asia, 2020 - academia.edu
… pathway for the absorption of dietary lipid digestion products; … phase, and concentration of
the surfactants influence the self-… 57 , the bioavailability of probucol in minipigs showed that …
the surfactants influence the self-… 57 , the bioavailability of probucol in minipigs showed that …
[HTML][HTML] Synergistic stabilization of emulsion gel by nanoparticles and surfactant enables 3D printing of lipid-rich solid oral dosage forms
J Johannesson, MM Pathare, M Johansson… - Journal of Colloid and …, 2023 - Elsevier
… formulation and design of suitable oral drug products. Co-administration of lipids enhance
the oral bioavailability … that could have appeared to influence the work reported in this paper. …
the oral bioavailability … that could have appeared to influence the work reported in this paper. …