[HTML][HTML] Recent advances in clinical diagnosis and pharmacotherapy options of membranous nephropathy

YN Wang, HY Feng, X Nie, YM Zhang, L Zou… - Frontiers in …, 2022 - frontiersin.org
… most common cause of nephrotic syndrome among adults, … of sensitive and specific
biomarkers and effective therapy for … summarized newer diagnosis biomarkers including PLA 2 R …

[HTML][HTML] “Presumed” primary focal segmental glomerulosclerosis: a novel nuance for steroid therapy

RJ Glassock, FC Fervenza - Kidney International Reports, 2022 - kireports.org
… Furthermore, we still lack a definitive serum or urinary biomarker with high sensitivity or … to
have primary FSGS based on clinical criteria (nephrotic syndrome, ie, proteinuria level ≥3.5 g/…

[HTML][HTML] Mining the biomarker potential of the urine peptidome: From amino acids properties to proteases

F Trindade, AS Barros, J Silva, A Vlahou… - International Journal of …, 2021 - mdpi.com
… In this paper, we appraise the value of urine peptidomics in biomarker research through a
biomarker not only for kidney diseases but also for extra-renal conditions, as a step forward

Novel biomarkers for lupus nephritis in the “OMICS” era

R Dias, UG Hasparyk, MP Lopes… - Current medicinal …, 2021 - ingentaconnect.com
… proteinuria and hematuria to nephrotic syndrome, cast excretion, … ideal biomarker since it is
unlikely that a sole biomarker will … Therefore, the most viable way to better assess LN patients …

[HTML][HTML] Circulating miRNAs in extracellular vesicles related to treatment response in patients with idiopathic membranous nephropathy

IO Sun, YU Bae, H Lee, H Kim, JS Jeon, H Noh… - Journal of Translational …, 2022 - Springer
only for discriminating idiopathic membranous nephropathy (IMN) from idiopathic nephrotic
syndrome (INS), but also to predict the treatment … -miRNAs as biomarkers for IMN diagnosis. …

[HTML][HTML] Proteomics and extracellular vesicles as novel biomarker sources in peritoneal dialysis in children

C Trincianti, V Meleca, E La Porta, M Bruschi… - International Journal of …, 2022 - mdpi.com
nephrotic syndrome in the pediatric age leading to ESKD. They used a purified fraction of PDE
exosomes to avoid the risk of masking important biomarkers by … us to a step forward in the …

Blocking CHOP-dependent TXNIP shuttling to mitochondria attenuates albuminuria and mitigates kidney injury in nephrotic syndrome

SJ Park, Y Kim, C Li, J Suh… - Proceedings of the …, 2022 - National Acad Sciences
… In our genetic model of nephrotic syndrome (NS), we have identified CHOP (C/EBP
homologous protein)-TXNIP (thioredoxin-interacting protein) as critical molecular linkers between …

Pathophysiology and system biology of rat c-BSA induced immune complex glomerulonephritis and pathway comparison with human gene sequencing data

H Wu, B Jia, X Zhao, H Zhang, Z Li, W Wang… - International …, 2022 - Elsevier
… Immune-complex glomerulonephritis (ICGN) is a major cause of nephrotic syndrome in …
clinical features of immune-mediated nephrotic syndrome with gradual declining renal function, …

[HTML][HTML] Unbiased kidney-centric molecular categorization of chronic kidney disease as a step towards precision medicine

A Reznichenko, V Nair, S Eddy, D Fermin, M Tomilo… - Kidney International, 2024 - Elsevier
biologically meaningful disease categorization based on individual intrarenal molecular
characteristics, as a critical step toward developing personalized treatmentNephrotic Syndrome

Glomerular diseases in pregnancy: pragmatic recommendations for clinical management

F Fakhouri, N Schwotzer, G Cabiddu, J Barratt… - Kidney international, 2023 - Elsevier
… the use of a modified definition of nephrotic syndrome, whereby serum albumin below the
… /d are suggestive of nephrotic syndrome. Severe nephrotic syndrome would be defined by a …