PCV14 Comparative Effectiveness and Safety of High Dose of ORAL Anticoagulant in Patients with NON-Valvular Atrial Fibrillation

S Perreault, R Côté, S De Denus… - Value in Health, 2020 - valueinhealthjournal.com
… of low dose dabigatran and rivaroxaban relative to warfarin … , low dose apixaban presented
a better safety profile with risk … but an increasing risk of major bleeding. Conclusions: …

[HTML][HTML] Anticoagulants for stroke prevention in atrial fibrillation in elderly patients

A Schäfer, U Flierl, D Berliner, J Bauersachs - Cardiovascular drugs and …, 2020 - Springer
… of the four NOACs dabigatran, rivaroxaban, apixaban, and … , apixaban and edoxaban had
a lower risk of major bleeding … Of note, in a randomised placebo-controlled trial for low-dose

Non-vitamin K antagonist oral anticoagulants versus warfarin in patients with atrial fibrillation and peripheral artery disease: a systematic review and meta-analysis

XZ Liao, YH Fu, JY Ma, WG Zhu, P Yuan - Cardiovascular Drugs and …, 2020 - Springer
… rhythm, a combination of low-dose rivaroxaban (2.5 mg twice … of MI and major bleeding
compared with warfarin [14]. The … types of NOACs including dabigatran, rivaroxaban, apixaban, or …

Comparative effectiveness and safety of non–vitamin K antagonist oral anticoagulants in atrial fibrillation patients

W Zhu, Z Ye, S Chen, D Wu, J He, Y Dong, GYH Lip… - Stroke, 2021 - Am Heart Assoc
… NOACs versus one another among AF patients, suggesting that apixaban may be a better
choice compared with dabigatran or rivaroxaban in terms of the lower major bleeding risks. …

Clinical characteristics of apixaban prescription in AF patients with single dose-reduction criterion: the ASPIRE (efficAcy and safety of aPixaban in rEal-world practice …

JM Choi, SR Lee, S Kwon, HJ Ahn, KY Lee… - Frontiers in …, 2024 - frontiersin.org
low-dose edoxaban 15 mg in older adults with bleeding risk … increase in major bleeding in
the Japanese population (30). … plasma concentrations of rivaroxaban and apixaban in Asian …

… of the Effectiveness and Safety of Direct Oral Anticoagulants in Elderly Patients With Nonvalvular Atrial Fibrillation Who Are Not Candidates for Warfarin in Real-World …

CT Lo, F Niu, DA Fredriks, RL Hui - Journal of Cardiovascular …, 2022 - journals.lww.com
bleeding was comparable for patients taking apixaban … (ie, apixaban, dabigatran, edoxaban,
and rivaroxaban) in comparison … Fifth, we chose not to evaluate low-dose aspirin, as it is a …

Comparison of low-versus high-dose four-factor prothrombin complex concentrate (4F-PCC) for factor Xa inhibitor–associated bleeding: a retrospective study

HA Wilsey, AM Bailey, A Schadler… - Journal of Intensive …, 2021 - journals.sagepub.com
… for critical bleeding associated with apixaban or rivaroxaban and postoperative bleeding
for … We report numerically more VTE complications in the low-dose cohort, however, it is …

Benefits and Harms of Standard Versus Reduced‐Dose Direct Oral Anticoagulant Therapy for Older Adults With Multiple Morbidities and Atrial Fibrillation

KN Hayes, T Zhang, DH Kim, LA Daiello… - Journal of the …, 2023 - Am Heart Assoc
… DOAC initiators (apixaban, dabigatran, rivaroxaban) aged ≥… that, compared with placebo,
lowdose DOAC therapy with … significantly increasing risk of major bleeding. Guidelines have …

Development and validation of the DOAC score: a novel bleeding risk prediction tool for patients with atrial fibrillation on direct-acting oral anticoagulants

R Aggarwal, CT Ruff, S Virdone, S Perreault… - Circulation, 2023 - Am Heart Assoc
… ), with individuals taking dabigatran, edoxaban, rivaroxaban, and apixaban. To determine
generalizability … Performance of the algorithm was also assessed in the low-dose DOAC arm. …

[HTML][HTML] A real-world study of different doses of rivaroxaban in patients with nonvalvular atrial fibrillation

X Yan, L Zhang, D Zhang, X Wang - Medicine, 2024 - journals.lww.com
… with 15 and 20 mg/d (standard-dose) rivaroxaban in an Asian AF population, and … that the
risk of infarction was higher for low-dose rivaroxaban, while the risks of embolism and bleeding