… network of thick, highly-branched capillaries within islets (1, 10… foregut endoderm and acquire
their differentiated fate in a … at the interface between islet blood vessels and β-cells (31). As …

… Using genetic lineage tracing, transcriptome, and functional studies, we identified mesenchymal
populations with different roles during pancreatic development. Moreover, we showed …

… in pancreatic branching [18]. While loss of Cdc42 during early pancreatic development
suppresses … promotes specification of the early pancreas [37]; and later, to restrain branching and …

… structure and function of blood vessels in different endocrine … development, follicle architecture,
endothelial differentiation … Endocrine pancreatic islets are vascularized by a dense and …

… blood vessels, formed a dorsal pancreas, confirmed by the presence of Pdx-1-positive cells,
but fail to grow and differentiate … Loss of VEGF function leads to reduced epithelial branching…

… Early cell fate differentiation in pancreatic development. … differentiation while blocking
branching and proliferation of the … these blood vessels is crucial in promoting early pancreatic …

… development and function. Early during pancreas development, blood vessels are required
for pancreas spec… , they confine pancreas branching, differentiation, and growth. In the adult …

… Given the role of FAK-mediated ECM-integrin signaling in branching of the developing
pancreas, we studied the deposition of laminin (an integrin ligand) in the mutant …

… in islet cell differentiation during human pancreatic development … cell differentiation of the
developing human pancreas from … h is sufficient to significantly suppress PaSC activity and was …

… in between growing epithelial branches and contained some … density and localization control
acinar differentiation 18,46 , … an inhibitory effect of BMP7 on blood vessels development. …