[HTML][HTML] … a preceding 10-year period do not correlate with cognitive performance and hippocampal bloodbrain barrier permeability in cognitively normal late-middle …

A Bakhtiari, MB Vestergaard, K Benedek, B Fagerlund… - Geroscience, 2023 - Springer
… , we investigated the correlation between bloodbrain barrier (BBB) permeability, regional
atrophy rates of 0.2–0.5% [15,16,17]. It has been suggested that the medial temporal lobes

Hippocampal bloodbrain barrier permeability is related to the APOE4 mutation status of elderly individuals without dementia

WJ Moon, C Lim, IH Ha, Y Kim… - Journal of Cerebral …, 2021 - journals.sagepub.com
… We also hypothesized that BBB permeability would be … was independently correlated with
BBB permeability in our … regional structural atrophy. Furthermore, it has been recently reported …

[HTML][HTML] Quantitative water permeability mapping of blood-brain-barrier dysfunction in aging

JN Ford, Q Zhang, EM Sweeney, AE Merkler… - Frontiers in Aging …, 2022 - frontiersin.org
… al., 2018), we did not observe a statistically significant correlation. While our relatively small
… the possibility that k W may be more tightly correlated to age than CBF. We found that CBF in …

[HTML][HTML] Regional differences in blood-brain barrier permeability in cognitively normal elderly subjects: a dynamic contrast-enhanced MRI-based study

IH Ha, C Lim, Y Kim, Y Moon, SH Han… - Korean Journal of …, 2021 - ncbi.nlm.nih.gov
… because hippocampi and temporal lobes are best assessed … rating scale to assess medial
temporal lobar atrophy (MTLA) [… We found no correlation between the BBB permeability of …

[HTML][HTML] Associations between regional blood-brain barrier permeability, aging, and Alzheimer's disease biomarkers in cognitively normal older adults

M Denkinger, S Baker, B Inglis, S Kobayashi, A Juarez… - Plos one, 2024 - journals.plos.org
… whether abnormalities are limited to the medial temporal lobe (… two different modalities that
are highly correlated with each … and undergo atrophy in normal aging, but do not typically …

Blood-brain barrier breakdown is linked to tau pathology and neuronal injury in a differential manner according to amyloid deposition

Y Moon, HJ Jeon, SH Han… - Journal of Cerebral …, 2023 - journals.sagepub.com
that BBB permeability measured by albumin index was correlated with the severity of
medial temporal lobe atrophy 43 and by the experimental models of BBB leakage that induced …

[HTML][HTML] A preliminary report: the Hippocampus and surrounding temporal cortex of patients with schizophrenia have impaired blood-brain barrier

EL Goldwaser, RL Swanson, EJ Arroyo… - Frontiers in Human …, 2022 - frontiersin.org
… pathway(s) responsible for this degeneration remains unknown. Recent reports have … Since
BBB permeability increases with age, we explored a potential correlation between age and …

Dysfunction of the bloodbrain barrier in Alzheimer's disease: evidence from human studies

C Kurz, L Walker, BS Rauchmann… - Neuropathology and …, 2022 - Wiley Online Library
… is consensus that these events lead to cognitive deterioration … only regulate BBB permeability
and cerebral blood flow but are … from controls, 78 and correlated negatively with cognitive …

[HTML][HTML] Imaging the role of bloodbrain barrier disruption in normal cognitive ageing

ICM Verheggen, JJA de Jong, MPJ van Boxtel… - Geroscience, 2020 - Springer
… cortical atrophy (GCA) scale [57] and the medial temporal lobe … measure of the permeability
surface area product that indicates the … cSVD burden was demonstrated to correlate with both …

Increased blood-brain barrier permeability of the thalamus correlated with symptom severity and brain volume alterations in patients with schizophrenia

Y Cheng, T Wang, T Zhang, S Yi, S Zhao, N Li… - … Neuroscience and …, 2022 - Elsevier
… to test the hypothesis that greater BBB permeability in patients … , including vascular
degeneration of endothelial cells, … The PuL is mainly connected to the temporal lobe, and the …