Body mass index and molecular subtypes of colorectal cancer

N Murphy, CC Newton, M Song… - … the National Cancer …, 2023 - academic.oup.com
… hypermethylation of promoter CpG island sites, causing … However, no evidence of
heterogeneity by CIMP status was … age, sex, education, smoking, physical activity, regular use of …

Association between risk factors, molecular features and CpG island methylator phenotype colorectal cancer among different age groups in a Taiwanese cohort

KH Chen, LI Lin, CT Yuan, LH Tseng, YL Chao… - … Journal of Cancer, 2021 - nature.com
… CIMP-high CRC, a positive association between body mass index (BMI) (kg/… physical
activities, compared to CIMP-low/negative CRC. One meta-analysis also revealed that there was no

Epidemiology and molecular-pathologic characteristics of CpG Island methylator phenotype (CIMP) in colorectal cancer

SM Advani, MD Swartz, J Loree, JS Davis… - … colorectal cancer, 2021 - Elsevier
… an epigenetic phenotype in colorectal tumors characterized by significant hypermethylation
… Also, we found no differences in CIMP-H prevalence across methodologic subtypes, making …

Risk factors and incidence of colorectal cancer according to major molecular subtypes

L Wang, X He, T Ugai, K Haruki, CH Lo… - JNCI cancer …, 2021 - academic.oup.com
… instability (MSI), CpG island methylator phenotype (CIMP), and … Physical activity is calculated
by the product sum of the … ), family history of colorectal cancer (yes or no), history of lower …

Changes in DNA methylation after 6‐week exercise training in colorectal cancer survivors: A preliminary study

SH Hwang, DW Kang, MK Lee… - Asia‐Pacific Journal …, 2022 - Wiley Online Library
No imbalances in baseline characteristics between groups were observed. The changes on
PA, body composition, physical fitness … of CpG sites in relation to gene and CpG islands. (A) …

Combined individual participant data: highest-level evidence on obesity and colorectal cancer molecular subtypes

GA Colditz - JNCI: Journal of the National Cancer Institute, 2023 - academic.oup.com
… of body mass index (BMI) was remarkably consistent across KRAS, BRAF, CpG island
in adult life through healthy diet, physical activity, and limiting sugar-sweetened beverages. …

Risk factor profiles differ for cancers of different regions of the colorectum

L Wang, CH Lo, X He, D Hang, M Wang, K Wu… - Gastroenterology, 2020 - Elsevier
… for ascending colon cancer to 0.54 for sigmoid colon cancer. For proximal … CpG island
methylator phenotype … on specific physical activities and calculated total physical activity as the …

[HTML][HTML] Microsatellite instability and life style factors in sporadic colorectal cancer

N Atef, N Alieldin, G Sherif, I Loay… - … journal of cancer …, 2020 - ncbi.nlm.nih.gov
… of MSS/MSI-L colon cancer but not for MSI-H colon cancer. This relationship was not found
… of physical activity were associated with an increased risk of MSS/MSI-L colon cancer but no

Excessive body fat at a young age increases the risk of colorectal cancer: a systematic review and meta-analysis

X Lei, S Song, X Li, C Geng, C Wang - Nutrition and cancer, 2021 - Taylor & Francis
Body size, physical activity and risk of colorectal cancer with or without the CpG island
methylator phenotype (CIMP). PloS ONE. 2011;6(4):e18571doi:10.1371/journal.pone.0018571 …

Lifestyle factors affecting the occurrence, presentation, and mortality of colorectal cancer

C Chime - 2020 - search.proquest.com
… methylation of CpG islands, resulting in the CpG island methylator … Smoking also increased
the risk of colon cancers without … that physical activity reduces the risk of colon cancer overall, …