… Considering the results from preclinical investigations, we suggest that this enhanced
PAG-RVM-SpV functional connectivity in individuals with chronic orofacial neuropathic …

… chronic non-neuropathic pain, painful temporomandibular disorders (TMD), display alterations
in brainstem pain-modulating circuits… connectivity (FC) analyses to assess ongoing circuit …

… with chronic neuropathic pain, fluctuations in spontaneous pain are associated with
fluctuations in brainstem pain-modulation circuitry connectivity. That is, when pain intensity was …

… pain control system which account for the imbalance in the descending modulation during
… 101 of neuropathic rats. At the DRt, in the spared nerve injury model of neuropathic pain, we …

… neuropathic pain, the opioidergic modulation of brainstem … plasticity of brainstem pain control
circuits involving monoaminergic … in the functional connectivity of pain control centers of the …

… chronic neuropathic orofacial pain. Compared to controls, individuals with chronic pain show
enhanced positive functional connectivity … Furthermore, in neuropathic pain patients, as the …

… chronic neuropathic limb pain, compared to those without pain, we hypothesized altered
functional connectivity … with multiple sclerosis affected by chronic neuropathic pain, along with …

… Example of a main effect of pain score for a connection … pain score for each participant/condition,
and the vertical axis indicates the connectivity strength (β) for this particular connection. …

… 3 presents a dual network model of the human cortical sites which regulate brainstem output
in the … to the brainstem change across time. Chapter 4 bridges function and biochemistry, …

… of the brainstem/spinal cord in chronic pain as well as what elements of pain modulation
during … connectivity are associated with the expectation of pain and resulting expectation-based …