… Ultimately this impaired ability of HIV-1 specific CD8 T cells to … Cytomegalovirus vaccine
vectors were designed in the … maintain high frequency, effectordifferentiated, and broadly …

… addressed for the broad use of CAR T cell therapy. These include … Vaccination of CAR T
cell-treated mice with activated DCs pulsed with WT1 peptide, enhanced CAR T cell expansion …

… It can induce effective HIV-1-specific immunity to control … regions containing a wide range of
critical T- and B-cell epitopes of … HIV-1-specific T cell responses. J Transl Med. 2011;9:1-20.- …

… The frequency of HIV-1-specific CD8+ T cells remains stable over time in durably … Current
therapies can be broadly divided into traditional therapeutic vaccine approaches that seek to …

… methods to reliably generate T cell responses capable of broad recognition, and it … receptors,
or TCR. The … (53)) can become activated more easily and undergo clonal expansion much …

… of uniform HIV-1-specific CAR T cells not recognized by HIV [… bNAb injection, CD21 decoy
receptor neutralization and use … the latent HIV reservoir with wide tissue distribution and make …

… -engineered T cells, TCR gene-modified T cells, and vaccines. … A genome-wide DNA
methylation assessment evaluated the … stimulated CD8 T cells favored the elicitation and …

… (by rapid expansion of virus specific CD8 + T cells), to reduce … immunotherapy and to optimize
efficiency of vaccines. … such as CD8 + T cells depletion or broadly neutralizing antibodies …

… suppresses HIV viremia, but no vaccine or cure exists. Rare … research and discuss the
broader implications of this thesis. … expansion of virus-specific CD8 T cells, resulting in a biased …

… agents that prevent proliferation of latently infected T cells … The wide acceptance and
accessibility of ART in 1995 … demonstrated enhanced innate and HIV-1-specific immunity in vivo …