Oral vitamin D supplementation induces transcriptomic changes in rectal mucosa that are linked to anti-tumour effects

PG Vaughan-Shaw, G Grimes, JP Blackmur… - BMC medicine, 2021 - Springer
… We devised a 2-Phase in vivo approach, firstly to identify differentially expressed genes in
… Enrichment of pathways involved in cell migration and cell death validate published in vitro

Establishment and external verification of an oxidative stress-related gene signature to predict clinical outcomes and therapeutic responses of colorectal cancer

S Cao, C Chen, D Gu, Z Wang, G Xu - Frontiers in Pharmacology, 2023 - frontiersin.org
Objective: Accumulated evidence highlights the biological significance of oxidative stress in
tumorigenicity and progression of colorectal cancer (CRC). Our study aimed to establish a …

[HTML][HTML] Comprehensive proteomic signature and identification of CDKN2A as a promising prognostic biomarker and therapeutic target of colorectal cancer

QQ Wang, YC Zhou, YJZ Ge, G Qin, TF Yin… - World journal of …, 2022 - ncbi.nlm.nih.gov
… mechanisms of abnormal proliferation, differentiation, resistance to apoptosis and … analyses
in combination, we aimed to identify potential target proteins among numerous differentially …

[HTML][HTML] An integrative pan-cancer analysis illustrating the key role of LRP11 in cervical cancer

F Gu, F Xu, Z Pan, L Shi, J Yu, F Song, SF Huang… - Medicine, 2023 - journals.lww.com
Butyrate-induced in vitro colonocyte differentiation network model identifies ITGB1, SYK,
CDKN2A, CHAF1A, and LRP1 as the prognostic markers for colorectal cancer recurrence. Nutr …

[HTML][HTML] Rectal Cancer genes down-regulated by Vitamin D (3,200 IU only helped some)–RCT Aug 2021

PG Vaughan-Shaw, G Grimes, JP Blackmur… - BMC Med, 2021 - vitamindwiki.com
vitro gene expression and cancer cell growth. We sought to determine whether oral vitamin
D induces beneficial gene expression effects in human rectal epithelium and identifyidentify