Dangerous Liaisons: Interactions of Cryptococcus neoformans with Host Phagocytes
EA Gaylord, HL Choy, TL Doering - Pathogens, 2020 - mdpi.com
… neoformans may manipulate phagosome maturation to enhance its own … by macrophages
are degraded in the phagosome, C. neoformans uses at least three mechanisms to escape …
are degraded in the phagosome, C. neoformans uses at least three mechanisms to escape …
Core N-Glycan Structures Are Critical for the Pathogenicity of Cryptococcus neoformans by Modulating Host Cell Death
EJ Thak, SB Lee, S Xu-Vanpala, DJ Lee, SY Chung… - MBio, 2020 - Am Soc Microbiol
… Phagocyte escape is crucial for dissemination of C. neoformans … to block phagosome
acidification by staining macrophages … the phagosome by manipulating C. neoformans-containing …
acidification by staining macrophages … the phagosome by manipulating C. neoformans-containing …
Manipulation of host phagocytosis by fungal pathogens and therapeutic opportunities
… in host phagosome–fungal pathogen interactions, with a … to manipulate phagosome
maturation and to escape from … , actively manipulate the activation state of host macrophages by …
maturation and to escape from … , actively manipulate the activation state of host macrophages by …
Elements of dissemination in cryptococcosis
JM Bednarek, JCS Brown - mBio, 2024 - journals.asm.org
… escape is influenced by several virulence factors specific to C… an insufficient anti-inflammatory
macrophage response, the … phagosome pH has demonstrated that basic phagosomal pH …
macrophage response, the … phagosome pH has demonstrated that basic phagosomal pH …
Survival in macrophages induces enhanced virulence in Cryptococcus
… Evasion of host immunity is a central theme of Cn … and (b) by altering the cell surface to
manipulate the nature of subsequent … occurs in vivo and is influenced by phagosomal pH. mBio 2:…
manipulate the nature of subsequent … occurs in vivo and is influenced by phagosomal pH. mBio 2:…
Host–Pathogen Interactions and Correlated Factors That Are Affected in Replicative-Aged Cryptococcus neoformans
VKA Silva, S Min, K Yoo, BC Fries - Journal of Fungi, 2024 - mdpi.com
… phagolysosomes and can manipulate the phagosome pH. … replicate within the acidic
phagosome and to escape via a non-… interactions with macrophages [15], we hypothesized that C. …
phagosome and to escape via a non-… interactions with macrophages [15], we hypothesized that C. …
Macrophage Mediated Immunomodulation During Cryptococcus Pulmonary Infection
…, O Dutta, K Wang, A Rivera, C Xue - Frontiers in Cellular …, 2022 - frontiersin.org
… to interact with and manipulate host macrophages. These … This capsule plays the dual role
of “sword” by evading host immune … based on their PAMPs and engulf them into phagosomes. …
of “sword” by evading host immune … based on their PAMPs and engulf them into phagosomes. …
Fungal mechanisms of intracellular survival: what can we learn from bacterial pathogens?
PV Stuckey, FH Santiago-Tirado - Infection and Immunity, 2023 - Am Soc Microbiol
… (C) Phagosome escape examples: non-lytic exocytosis of C. … of the macrophage; yeast-to-hyphal
transition of C. albicans … manipulation of PIs may play a role in fungal escape from the …
transition of C. albicans … manipulation of PIs may play a role in fungal escape from the …
Real-time visualization of phagosomal pH manipulation by Cryptococcus neoformans in an immune signal-dependent way
EJ Santiago-Burgos, PV Stuckey… - Frontiers in Cellular …, 2022 - frontiersin.org
… interactions driving disease establishment is Cryptococcus’s … or Mycobacteria, escape from
the phagosome before it acidifies; … albicans’s phagosomes acidify faster in M1 macrophages …
the phagosome before it acidifies; … albicans’s phagosomes acidify faster in M1 macrophages …
Cryptococcus neoformans releases proteins during intracellular residence that affect the outcome of the fungal–macrophage interaction
…, PR Williamson, A Jedlicka, A Casadevall, C Coelho - …, 2022 - academic.oup.com
… phagosomes, may simply reflect the large size of the cryptococcal phagosome, and the fact
that C… We found that Yor1 is not involved in manipulating phagolysosomal pH. To assess any …
that C… We found that Yor1 is not involved in manipulating phagolysosomal pH. To assess any …