Yeast–amoeba interaction influences murine cryptococcosis

…, JC Sa, DG Ramos, DAV Marques, C Furst… - Microbes and …, 2023 - Elsevier
… The remaining yeasts, with competent evasion mechanisms … internalization (presence of
phagosome-like containing the … expression of Fas on macrophage surfaces, which favoured …

Loss of the scavenger receptor MARCO results in uncontrolled vomocytosis of fungi from macrophages

CU Onyishi, Y Jeon, G Fejer… - European Journal of …, 2024 - Wiley Online Library
interaction between MARCO, actin organisation and vomocytosis, we hypothesized that one
role for MARCO may be to sense phagosomal … showing to block phagosome fusion with the …

The Antimicrobial Peptide MK58911-NH2 Acts on Planktonic, Biofilm, and Intramacrophage Cells of Cryptococcus neoformans

JL Singulani, LT Oliveira, MD Ramos… - Antimicrobial Agents …, 2021 - Am Soc Microbiol
… host, Cryptococcus spp. can proliferate, transfer, and escape from macrophages lytically or
… host’s fungi are partially determined by macrophage-pathogen interactions (38). In our study, …

“We've got to get out”—Strategies of human pathogenic fungi to escape from phagocytes

J Sonnberger, L Kasper, T Lange… - Molecular …, 2024 - Wiley Online Library
… in the host phagosome following phagocytosis and even escape from macrophages. In this
… Consequently, pathogens may manipulate cell death pathways into different direction to …

Faster Cryptococcus Melanization Increases Virulence in Experimental and Human Cryptococcosis

HR de Sousa, GP de Oliveira Jr, SO Frazão… - Journal of Fungi, 2022 - mdpi.com
… positively with LC3-associated phagocytosis evasion, virulence in Galleria mellonella and
… proportion of macrophages with LC3 recruitment to at least one phagosome containing C. …

Global trends in Cryptococcus and its interactions with the host immune system: a bibliometric analysis

S Tang, R Hao, X Liu, H He, Y Tian, T Jing… - Frontiers in …, 2024 - frontiersin.org
… survival through facilitation of immune evasion from the host (4… the Cryptococcus capsule
can prompt macrophage apoptosis … evasion and the propagation mechanisms of Cryptococcus. …

[PDF][PDF] A double edged sword: Interferon-γ treatment worsens host outcomes in mouse models of pulmonary infection with C. neoformans

J Rudman - 2021 - etheses.whiterose.ac.uk
interactions with C. neoformans, as immune responses in pulmonary cryptococcosis are
macrophage… Controversially, interferon-γ worsened J774 control of intracellular C. neoformans. I …

Developing novel host-based therapies targeting microbicidal responses in macrophages and neutrophils to combat bacterial antimicrobial resistance

K Watson, CD Russell, JK Baillie, K Dhaliwal… - Frontiers in …, 2020 - frontiersin.org
… Impaired pathogen handling by … phagosomal maturation contributing to intracellular survival
(19), while others that are more readily killed may escape killing in subsets of macrophages, …

An in vitro model to study the naïve human peripheral blood mononuclear cell response to Cryptococcus neoformans infection

K Pline, SA Johnston - bioRxiv, 2020 - biorxiv.org
manipulate the intracellular niche of phagocytes for replication and dissemination. The
interaction of macrophages … neoformans likely colonises monocytes and macrophages to escape

The Nature of the Fungal Cargo Induces Significantly Different Temporal Programmes of Macrophage Phagocytosis

NAR Gow, MF Alonso, JM Bain, FM Rudkin… - Available at SSRN … - papers.ssrn.com
evasion mechanisms. Therefore, simultaneous assessment … differences in the rates of
engulfment and phagosome 106 … instrumental in determining the outcomes of interactions with …