Transitional changes in the structure of C-reactive protein create highly pro-inflammatory molecules: Therapeutic implications for cardiovascular diseases
J Zeller, B Bogner, JD McFadyen, J Kiefer… - Pharmacology & …, 2022 - Elsevier
… C-reactive protein (CRP) is the prototypic acute-phase … of inflammation and predictor of
cardiovascular risk. However, … mediator in atherosclerosis and cardiovascular diseases. The ‘…
cardiovascular risk. However, … mediator in atherosclerosis and cardiovascular diseases. The ‘…
[HTML][HTML] C‑reactive protein and cardiovascular disease: From animal studies to the clinic
Y Fu, Y Wu, E Liu - Experimental and therapeutic …, 2020 - spandidos-publications.com
… C‑reactive protein (CRP) and cardiovascular disease (CVD) have long been important
research topics. CRP is an acute phase protein, while CVD is an inflammatory condition. The …
research topics. CRP is an acute phase protein, while CVD is an inflammatory condition. The …
High sensitivity C-reactive protein (hsCRP) and its implications in cardiovascular outcomes
… new biomarkers for the so called residual inflammatory risk … identified; indeed, many different
molecules involved in the … on C-reactive protein and benefits for cardiovascular disease …
molecules involved in the … on C-reactive protein and benefits for cardiovascular disease …
C-reactive protein and its structural isoforms: an evolutionary conserved marker and central player in inflammatory diseases and beyond
JD McFadyen, J Zeller, LA Potempa… - … other body fluid proteins, 2020 - Springer
… as a pattern recognition molecule that binds to damaged … cardiovascular risk, combined
with the data that therapies that reduce CRP levels result in the reduction of cardiovascular risk…
with the data that therapies that reduce CRP levels result in the reduction of cardiovascular risk…
[HTML][HTML] Therapeutic lowering of C-reactive protein
RV Jimenez, AJ Szalai - Frontiers in immunology, 2021 - frontiersin.org
… class of pattern recognition molecules with the same or … heart disease in ostensibly healthy
people. Conclusive evidence for CRP causality in human CVD is still lacking [for more insight …
people. Conclusive evidence for CRP causality in human CVD is still lacking [for more insight …
[HTML][HTML] C-reactive protein as a risk marker for post-infarct heart failure over a multi-year period
I Świątkiewicz, P Magielski, J Kubica - International Journal of Molecular …, 2021 - mdpi.com
… Our findings provide additional insights with relevance to recent trials on the effectiveness
of anti-inflammatory therapies for reducing risk of HF and cardiovascular events. Existing …
of anti-inflammatory therapies for reducing risk of HF and cardiovascular events. Existing …
[HTML][HTML] Novel biomarkers of atherosclerotic vascular disease—Latest insights in the research field
… Intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion protein 1 (… C-reactive
protein (CRP), fibrinogen, uric acid, and lipoprotein (a) (Lp <a>) are cardiovascular risk …
protein (CRP), fibrinogen, uric acid, and lipoprotein (a) (Lp <a>) are cardiovascular risk …
[HTML][HTML] Update advances on C-reactive protein in COVID-19 and other viral infections
Y Luan, C Yin, Y Yao - Frontiers in immunology, 2021 - frontiersin.org
… molecule, CRP is usually combined with specific molecular configurations (pathogen related
molecular … variants is associated with the elevated mortality risk of heart diseases (28, 29). …
molecular … variants is associated with the elevated mortality risk of heart diseases (28, 29). …
Monomeric C‐reactive protein: a novel biomarker predicting neurodegenerative disease and vascular dysfunction
… bowel disease (IBD). A substantial influence on cardiovascular disease pathogenesis seems
to … protein-1 (MCP-1), intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion …
to … protein-1 (MCP-1), intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion …
[HTML][HTML] Inflammation and cardiovascular disease: From mechanisms to therapeutics
… (MI) had elevated high-sensitivity C-reactive protein (hsCRP), a common measure of low…
molecules such as intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule…
molecules such as intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule…