Transitional changes in the structure of C-reactive protein create highly pro-inflammatory molecules: Therapeutic implications for cardiovascular diseases

J Zeller, B Bogner, JD McFadyen, J Kiefer… - Pharmacology & …, 2022 - Elsevier
C-reactive protein (CRP) is the prototypic acute-phase … of inflammation and predictor of
cardiovascular risk. However, … mediator in atherosclerosis and cardiovascular diseases. The ‘…

[HTML][HTML] Creactive protein and cardiovascular disease: From animal studies to the clinic

Y Fu, Y Wu, E Liu - Experimental and therapeutic …, 2020 - spandidos-publications.com
Creactive protein (CRP) and cardiovascular disease (CVD) have long been important
research topics. CRP is an acute phase protein, while CVD is an inflammatory condition. The …

High sensitivity C-reactive protein (hsCRP) and its implications in cardiovascular outcomes

A Denegri, G Boriani - Current Pharmaceutical Design, 2021 - ingentaconnect.com
new biomarkers for the so called residual inflammatory risk … identified; indeed, many different
molecules involved in the … on C-reactive protein and benefits for cardiovascular disease

C-reactive protein and its structural isoforms: an evolutionary conserved marker and central player in inflammatory diseases and beyond

JD McFadyen, J Zeller, LA Potempa… - … other body fluid proteins, 2020 - Springer
… as a pattern recognition molecule that binds to damaged … cardiovascular risk, combined
with the data that therapies that reduce CRP levels result in the reduction of cardiovascular risk

[HTML][HTML] Therapeutic lowering of C-reactive protein

RV Jimenez, AJ Szalai - Frontiers in immunology, 2021 - frontiersin.org
… class of pattern recognition molecules with the same or … heart disease in ostensibly healthy
people. Conclusive evidence for CRP causality in human CVD is still lacking [for more insight

[HTML][HTML] C-reactive protein as a risk marker for post-infarct heart failure over a multi-year period

I Świątkiewicz, P Magielski, J Kubica - International Journal of Molecular …, 2021 - mdpi.com
… Our findings provide additional insights with relevance to recent trials on the effectiveness
of anti-inflammatory therapies for reducing risk of HF and cardiovascular events. Existing …

[HTML][HTML] Novel biomarkers of atherosclerotic vascular diseaseLatest insights in the research field

CA Adam, DL Șalaru, C Prisacariu, DTM Marcu… - … journal of molecular …, 2022 - mdpi.com
… Intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion protein 1 (… C-reactive
protein (CRP), fibrinogen, uric acid, and lipoprotein (a) (Lp <a>) are cardiovascular risk

[HTML][HTML] Update advances on C-reactive protein in COVID-19 and other viral infections

Y Luan, C Yin, Y Yao - Frontiers in immunology, 2021 - frontiersin.org
molecule, CRP is usually combined with specific molecular configurations (pathogen related
molecular … variants is associated with the elevated mortality risk of heart diseases (28, 29). …

Monomeric Creactive protein: a novel biomarker predicting neurodegenerative disease and vascular dysfunction

Y Pastorello, RO Carare, C Banescu… - Brain …, 2023 - Wiley Online Library
… bowel disease (IBD). A substantial influence on cardiovascular disease pathogenesis seems
to … protein-1 (MCP-1), intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion …

[HTML][HTML] Inflammation and cardiovascular disease: From mechanisms to therapeutics

A Alfaddagh, SS Martin, TM Leucker, ED Michos… - American journal of …, 2020 - Elsevier
… (MI) had elevated high-sensitivity C-reactive protein (hsCRP), a common measure of low…
molecules such as intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule