… Murine models of infection indicate that exhausted CD8 + T cells (T EX ) derive from … of the
interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. …

… during CD8 + T cell homeostasis and activation, and focus on the crosstalk between cell
signaling … of stimulation, and can modulate the effector function of T cells upon viral infection [ …

… kill target cells while also retaining the capacity to patrol infected … Indeed, deletion of CD8 +
T cells in SIV-infected macaques … that CD8 + T cells unable to completely clear infected cells …

… In conclusion, MT infections contribute to decreased T cell glycolytic metabolism through
several mechanisms. Despite that the knowledge is sparse, such changes may further have …

… from 12 studies of CD8 T cells in cancer and infection, we defined a shared … T cell states
across models. Experimental dissection of acute and chronic viral infection using single-cell …

… Here we show that CMV proteins UL36 and M36 protect infected cells from CD8 T cell
control by inhibiting Casp8-dependent apoptosis. We developed a set of methods to in vitro …

… CD8 + T cells overcome numerous tolerance mechanisms, including thymic selection and T
cell activation requirements, to exert inappropriate effector … CD8 + T cells in chronic infection …

… resistance mechanisms in T cell–infiltrated, ICB-refractory patients is limited. To better
understand ICB resistance in T cell–… signatures from acute and chronic LCMV infection. (K and L) …

… We demonstrate synergy between CD4 and CD8 T cells in promoting the survival of infected
… T cell help. We hypothesize that CD8 T cells require CD4 T cell help to develop into effector …

… CD8 T cells and initiating their effector functions. Upon recognition of infected cells, CD8 T
cells … Effector CD8 T cells target and eliminate HIVinfected cells, contributing to the control of …