[HTML][HTML] The role of granzyme B containing cells in the progression of chronic obstructive pulmonary disease
WD Kim, HS Chi, KH Choe, WS Kim… - … respiratory diseases, 2020 - ncbi.nlm.nih.gov
… GzmB + and CD8 + cells on alveolar wall of surgically resected lungs … cells than healthy
smokers and it was hypothesized that an insufficient number of regulatory T cells to CD8 + T cell …
smokers and it was hypothesized that an insufficient number of regulatory T cells to CD8 + T cell …
Effects of combustible cigarettes and heated tobacco products on immune cell-driven inflammation in chronic obstructive respiratory diseases
N Kastratovic, I Cekerevac, V Sekerus… - Toxicological …, 2024 - academic.oup.com
… Similarly, CCs increased presence of alveolotoxic, IFN-γ- and IL-17-producing CD3+CD8+CTLs
in the inflamed lungs of experimental animals (Fig.4C-D, p<0.001). In addition to Th1 …
in the inflamed lungs of experimental animals (Fig.4C-D, p<0.001). In addition to Th1 …
Anomalous epithelial variations and ectopic inflammatory response in chronic obstructive pulmonary disease
N Watanabe, Y Fujita, J Nakayama, Y Mori… - … of Respiratory Cell …, 2022 - atsjournals.org
… lung resident cell types and inflammatory cells that contribute to COPD progression, we profiled
57,918 cells from lungs of patients with COPD, smokers … and CD8 + T cells into the lungs …
57,918 cells from lungs of patients with COPD, smokers … and CD8 + T cells into the lungs …
Does Chronic Obstructive Pulmonary Disease Originate from Different Cell Types?
… At both onset and progression, CD4 + and CD8 + T cells are increased in the lungs of subjects
with COPD (74–76). Similarly… CD8 + T-lymphocytes in peripheral airways of smokers with …
with COPD (74–76). Similarly… CD8 + T-lymphocytes in peripheral airways of smokers with …
[HTML][HTML] The role of oxidised self-lipids and alveolar macrophage CD1b expression in COPD
MP Ween, JB White, HB Tran, V Mukaro, C Jones… - Scientific reports, 2021 - nature.com
… Chronic obstructive pulmonary disease (COPD) is incurable and … presence of cancer, lung
function, smoking status and pack year … infiltration of activated CD8+ cytotoxic T-cells in COPD …
function, smoking status and pack year … infiltration of activated CD8+ cytotoxic T-cells in COPD …
[HTML][HTML] Identification of biomarkers associated with clinical severity of chronic obstructive pulmonary disease
J Zhang, C Zhu, H Gao, X Liang, X Fan, Y Zheng… - PeerJ, 2020 - peerj.com
… COPD is defined as a chronic inflammatory lung disease. We chose IL-6, IL-8, TNF-α, and
… in the non-smoker and COPD I-II groups, and TLR2 in mononuclear cells of the peripheral …
… in the non-smoker and COPD I-II groups, and TLR2 in mononuclear cells of the peripheral …
[HTML][HTML] Update in chronic obstructive pulmonary disease 2019
… of CD8 + T cells. This was associated with … Smoking impairs the immunomodulatory capacity
of lung-resident mesenchymal stem cells in chronic obstructive pulmonary disease. Am J …
of lung-resident mesenchymal stem cells in chronic obstructive pulmonary disease. Am J …
[HTML][HTML] COPD, pulmonary fibrosis and ILAs in aging smokers: the paradox of striking different responses to the major risk factors
B Beghé, S Cerri, LM Fabbri, A Marchioni - International Journal of …, 2021 - mdpi.com
… pulmonary diseases: chronic obstructive pulmonary disease (COPD), interstitial lung
abnormalities (ILAs), and idiopathic pulmonary fibrosis … with impaired cytotoxicity of CD8 T-cells …
abnormalities (ILAs), and idiopathic pulmonary fibrosis … with impaired cytotoxicity of CD8 T-cells …
[HTML][HTML] Single-cell transcriptomics highlights immunological dysregulations of monocytes in the pathobiology of COPD
Q Huang, Y Wang, L Zhang, W Qian, S Shen… - Respiratory …, 2022 - Springer
… Chronic obstructive pulmonary disease (COPD) is a common … -cell transcriptomic data
of more than 65,000 cells in lung … of ligands that promote CD8 + T-cell and NKC cytotoxic …
of more than 65,000 cells in lung … of ligands that promote CD8 + T-cell and NKC cytotoxic …
More severe lung lesions in smoker patients with active pulmonary tuberculosis were associated with peripheral NK cell subsets
Y Rao, W Cao, J Qu, X Zhang, J Wang, J Wang, G Li… - Tuberculosis, 2023 - Elsevier
… Chronic obstructive pulmonary disease … Our findings reveal a potential role of NK cells in
the lung pathology caused … the smoker and non-smoker groups in the percentages of CD8 + T …
the lung pathology caused … the smoker and non-smoker groups in the percentages of CD8 + T …