Asthma-chronic obstructive pulmonary disease overlap

S Sharma, S Khurana… - Immunology and …, 2020 - immunology.theclinics.com
… Global Initiative for Chronic Obstructive Lung Disease (GOLD… 10 pack/years of tobacco
smoking or biomass fuel exposure; (… 3) peripheral blood eosinophil count of at least 200 cells/mL. …

… Breath Condensate as Fingerprints of Asthma, Chronic Obstructive Pulmonary Disease and Asthma–Chronic Obstructive Pulmonary Disease Overlap: A Critical …

B Seyfinejad, E Nemutlu, A Taghizadieh… - Biomarkers in …, 2023 - Taylor & Francis
… The CD8 + (T cytotoxic) and the CD4 + (T helper) cells are … diseases involve the same cells
and structures in the lungs. … smokers, former smokers or never-smokers controls because …

Computational Deconvolution of Cell Type-Specific Gene Expression in COPD and IPF Lungs Reveals Disease Severity Associations

MH Ryu, JH Yun, K Kim, M Gentili, A Ghosh, F Sciurba… - medRxiv, 2024 - medrxiv.org
… Why does an aging smoker’s lung develop idiopathic 498 pulmonary fibrosis and not … CD8
+ T cells in chronic obstructive pulmonary disease lung. American Journal of 528 Respiratory

Endoplasmic reticulum stress: a vital process and potential therapeutic target in chronic obstructive pulmonary disease

H Peng, Q Zhou, J Liu, Y Wang, K Mu, L Zhang - Inflammation Research, 2023 - Springer
… in the lungs, with many more CD8 + cells (Tc1 cells) than CD4 + cells (Th1 and Th17 cells) […
species, and cigarette smoke) induce airway epithelial cells to release neutrophilic mediators …

The lymphatic vasculature in lung function and respiratory disease

A Trivedi, HO Reed - Frontiers in Medicine, 2023 - frontiersin.org
Chronic obstructive pulmonary disease (COPD) is most … by cigarette smoking and is
characterized by progressive respiratory … endothelial cells, and animal models for manipulating …

Single cell RNA sequencing identifies IGFBP5 and QKI as ciliated epithelial cell genes associated with severe COPD

X Li, G Noell, T Tabib, AD Gregory, HE Trejo Bittar… - Respiratory …, 2021 - Springer
Chronic obstructive pulmonary disease (COPD) is a common … single-cell transcriptomes of
cell populations from lung tissue … We identified ciliated and CD8 + T cells as prominent cell

Airway hyperresponsiveness, inflammation, and pulmonary emphysema in rodent models designed to mimic exposure to fuel oil–derived volatile organic compounds …

Ó Amor-Carro, KM White, R Fraga-Iriso… - Environmental …, 2020 - ehp.niehs.nih.gov
smoke–driven emphysema in chronic obstructive pulmonary … role of CD 8 + T cells as
potential inducers of alveolar septal cellCD8+ve cells in the lungs of smokers with chronic

Mechanisms of airway epithelial injury and abnormal repair in asthma and COPD

KL Raby, C Michaeloudes, J Tonkin, KF Chung… - Frontiers in …, 2023 - frontiersin.org
… cause airway diseases, including chronic obstructive pulmonaryCD8+ T cells are increased
in COPD and numbers inversely … of senescent cells may exacerbate lung inflammation and …

Current perspectives on biological therapy for COPD

AK Yadav, W Gu, T Zhang, X Xu… - … Obstructive Pulmonary …, 2023 - Taylor & Francis
smoking in the absence of a stimulus such as viral infection [Citation59]. The connection
between CXCR3, which is generated by CD8+ cytotoxic T cellschronic obstructive lung disease

Treatment Strategies for Non-Small-Cell Lung Cancer with Comorbid Respiratory Disease; Interstitial Pneumonia, Chronic Obstructive Pulmonary Disease, and …

R Otoshi, S Ikeda, T Kaneko, S Sagawa, C Yamada… - Cancers, 2024 - mdpi.com
… that COPD patients and current smokers had longer PFS [73]… in ex-smokers with COPD
complications than in ex-smokers … Th2 cells and increased expression of PD-1 on CD8+ T cells