CGRP Inhibitors for the Treatment of Migraine
S Walter, ME Bigal - Successful Drug Discovery, 2021 - Wiley Online Library
… neurotransmission in the spinal cord during peripheral inflammation. Can. J. … P and
calcitonin gene-related peptide in primary afferent neurons during peripheral inflammation. …
calcitonin gene-related peptide in primary afferent neurons during peripheral inflammation. …
Network pharmacology and metabolomics studies on antimigraine mechanisms of da chuan xiong Fang (DCXF)
S Ma, L Zheng, X Lin, Y Feng, M Yang… - Evidence‐Based …, 2021 - Wiley Online Library
… migraines through upregulation of 5-HT levels and downregulation of L-Glu levels and calcitonin
gene-related peptide … Most of the intersecting genes were 5-hydroxytryptamine receptor …
gene-related peptide … Most of the intersecting genes were 5-hydroxytryptamine receptor …
Environmental enrichment alleviates hyperalgesia by modulating central sensitization in a nitroglycerin-induced chronic migraine model of mice
L Wang, X Liu, C Zhu, S Wu, Z Li, L Jing… - … Journal of Headache …, 2024 - Springer
… , calcitonin gene-related peptide (CGRP) and inflammatory … be driven by neuroinflammation
in the peripheral and CNS. … A Venn diagram was generated at the intersection of enriched …
in the peripheral and CNS. … A Venn diagram was generated at the intersection of enriched …
Pain, Motivation, migraine, and the microbiome: New frontiers for opioid systems and disease
… Yet how, where, and what specific neurocircuitry coordinates this intersection of stress, …
Here we show that the opioid system can be involved in peripheral and/or central regulation …
Here we show that the opioid system can be involved in peripheral and/or central regulation …
[HTML][HTML] Burden of migraine with acute medication overuse or psychiatric comorbidities and treatment with CGRP pathway-targeted monoclonal antibodies: A review
C Rhyne, JM Cohen, MJ Seminerio, K Carr… - Medicine, 2023 - journals.lww.com
… calcitonin gene-related peptide pathway plays a key role in the pathophysiology of migraine…
[ 13 ] CGRP is expressed in the central and peripheral nervous system and may modulate …
[ 13 ] CGRP is expressed in the central and peripheral nervous system and may modulate …
Migraine-a borderland disease to epilepsy: near it but not of it
…, European Headache Federation School of … - … Journal of Headache …, 2024 - Springer
… migraine aura, or neurotransmitters, mainly Glutamate and GABA, which represent important
roles in triggering migraine … the group of familial hemiplegic migraines, which are caused by …
roles in triggering migraine … the group of familial hemiplegic migraines, which are caused by …
Antibody-Based Biotherapeutics in Migraine
WPJ van Oosterhout - Pharmaceutical Biotechnology: Fundamentals and …, 2024 - Springer
… Migraine attacks are associated with trigeminal release of … vasodilatory neuropeptide
calcitonin gene-related peptide (… Peripheral sensitization sustains neurogenic inflammation and …
calcitonin gene-related peptide (… Peripheral sensitization sustains neurogenic inflammation and …
Mechanisms Underlying Migraine Headache Pathophysiology: Novel Insights From Preclinical Models
JE Lackovic - 2021 - utd-ir.tdl.org
… in headache for decades, particularly in regards to peripheral sensitization 21-25 and neurogenic
inflammation … target of triptans and calcitonin gene-related peptide (CGRP) antagonists …
inflammation … target of triptans and calcitonin gene-related peptide (CGRP) antagonists …
Antinociceptive effect of the calcitonin gene-related peptide receptor antagonist BIBN4096BS in mice with bacterial cystitis
N Montalbetti, MG Dalghi… - American Journal …, 2023 - journals.physiology.org
… calcitonin gene-related peptide (CGRP) at their peripheral … to 121.5 µm between intersections
was superimposed upon … CGRP plays a paramount role in migraine pathogenesis (14). …
was superimposed upon … CGRP plays a paramount role in migraine pathogenesis (14). …
Orofacial migraine or neurovascular orofacial pain from pathogenesis to treatment
… to typify the intersection between headache and orofacial … When peripheral anatomy remains
insufficient to explain a low … anti-migraine therapy, Calcitonin Gene Related Peptide (CGRP…
insufficient to explain a low … anti-migraine therapy, Calcitonin Gene Related Peptide (CGRP…