Migraine pharmacological treatment and cognitive impairment: risks and benefits

M Russo, MA De Rosa, D Calisi, S Consoli… - International Journal of …, 2022 - mdpi.com
… The calcitonin-gene-related peptide (CGRP) is a 37-aa … CALCA gene, mostly in the peripheral
nervous system and CNS [181]. … on the intersections shared by dementia and migraine to …

Gepants—a long way to cure: a narrative review

C Altamura, N Brunelli, M Marcosano, L Fofi… - Neurological …, 2022 - Springer
calcitonin gene-related peptide (CGRP)-targeted therapies came as a real revolution in
migraine … Finally, there is a complex intersection between CGRP and cortical spreading …

The role of the kynurenine signaling pathway in different chronic pain conditions and potential use of therapeutic agents

F Jovanovic, KD Candido, NN Knezevic - International journal of …, 2020 - mdpi.com
… infection and associated pro-inflammatory cytokines, such as … , such as calcitonin gene-related
peptide (CGRP), neurokinin … -mediated migraine modulation at the central and peripheral

Human models

S Younis, TP Do, M Ashina - Monoclonal Antibodies in Headache: From …, 2021 - Springer
… of calcitonin gene-related peptide (CGRP) to migraine … suggest a peripheral site of action of
CGRP in migraine induction. … Capsaicin produces neurogenic inflammation and vasodilation …

Refractory migraine: a cerebrovascular disease?

D Fiorella, AS Arthur, H Yuan, P Bhogal… - Journal of …, 2024 - jnis.bmj.com
migraine. The vasoactive molecules, like CGRP and nitric oxide, which induce migraines
also activate neurogenic inflammationinflammation, such as vasoactive intestinal peptide, do …

Migraine Mechanisms: In Relation to the Premonitory Phase and CGRP/CGRP Receptor Antagonists

E Awaki, T Takeshima - Brain and Nerve= Shinkei Kenkyu no …, 2021 - europepmc.org
… hand, calcitonin gene-related peptide (CGRP) has now been firmly established as a key
player in migraine. … inflammation, and peripheral sensitization are likely to be the most relevant …

The tachykinin hemokinin-1 as a mediator in neuronal-and immune functions in mouse models of pain, arthritis, and dermatitis

H Ágnes - 2021 - pea.lib.pte.hu
inflammation when inflammatory neuropeptides like tachykinins (substance P = SP and
neurokinin-A = NKA) and calcitonin gene related peptide (… peripheral and central mechanisms20. …

Neuronal complexity is attenuated in preclinical models of migraine and restored by HDAC6 inhibition

Z Bertels, H Singh, I Dripps, K Siegersma, AF Tipton… - Elife, 2021 - elifesciences.org
… antagonists against calcitonin gene-related peptide (CGRP) … sites for pain processing in the
peripheral nervous system. No … a significant decrease in total intersections after chronic NTG …

Neuronal complexity is attenuated in chronic migraine and restored by HDAC6 inhibition

Z Bertels, H Singh, I Dripps, K Siegersma, AF Tipton… - bioRxiv, 2020 - biorxiv.org
… of antibodies against calcitonin gene related peptide (CGRP) … intersections. To ensure that
this effect was associated with … spinal cord, an important site for peripheral but not head-pain …

[PDF][PDF] Calcitonin gene related peptide modified mesenchymal stem cells reduce restenosis after carotid balloon injury in rats.

P Chen, S Ma - Biocell, 2022 - cdn.techscience.cn
… Abstract: This work aimed to investigate the effects of calcitonin gene-related peptide (CGRP…
Dynamics of replication proteins during lagging strand synthesis: A crossroads for genomic …