… Here, we review what is known about Ca 2+ signaling and how this fundamental second …
to cell proliferation, apoptosis, and autophagy. We also explore the intersections of Ca 2+ and …

… silymarin apoptotic activity. Malignant p53 negative cells show only minimal apoptosis when
… Silymarin has the ability to inhibit CA isoforms CA I and CA II. However, we could not find …

… calcium hypothesis of AD posits that activation of the amyloidogenic pathway affects neuronal
Ca 2… 2+ -induced apoptosis, was overexpressed in AD models compared to controls [195]. …

… , calcium transport, and apoptosis. While VDAC’s role in shuttling metabolites between the
cytosol and mitochondria is well established, there is a growing interest in understanding the …

… Mitochondria play key roles in ATP supply, calcium homeostasis, redox balance control
and apoptosis, which in neurons are fundamental for neurotransmission and to allow synaptic …

… microplastics-induced Ca 2 + overload was integral to prevent hepatocyte apoptosis and S
… Collectively, this study reveals a regulatory paradigm that links ROS with AMPK and Ca 2 + …

… In critical periods, the glutamate storm and calcium overload via NMDAR could trigger local
… strongly support this hypothesis. We have observed increased apoptotic susceptibility in …

… The calcium hypothesis of AD posits that activation of the amyloidogenic pathway remodels
neuronal calcium signaling, and alters normal calcium … of apoptosis by mitochondrial calcium …

… Third, we briefly describe how and why viruses depend on ionic calcium. Fourth, we … of how
calcium metabolism mediates disease and bodily defences. Fifth, we address the hypothesis …

… Based on these studies, we hypothesized that enrichment of the host cytoplasm with Ca 2+
might prompt ADAM10 and MAPK activation. To tackle this hypothesis, HeLa cells were …