COX‐2 Inhibition Antagonizes Intra‐Accumbens 2‐Arachidonoylglycerol–Mediated Reduction in Ethanol SelfAdministration in Rats

FJ Pavon, I Polis, DG Stouffer… - Alcoholism: Clinical …, 2020 - Wiley Online Library
… ), are synthesized on demand and bind to cannabinoid receptors (CB 1 and CB 2 ) to exert
… on operant self-administration induced by intra-NAc shell infusions of SR141716A and 2-AG…

[HTML][HTML] Cannabinoid-induced conditioned place preference, intravenous self-administration, and behavioral stimulation influenced by ghrelin receptor antagonism in …

C Charalambous, T Havlickova, M Lapka… - International Journal of …, 2021 - mdpi.com
administration of alcohol extract of Cannabis sativa [15], as well as a single intraperitoneal
injection of synthetic cannabinoid CB1 receptorreceptors since the antagonist (SR141716A) …

Attenuation of oleoylethanolamide-induced reduction of alcohol consumption in adult rats exposed intermittently to alcohol during adolescence

L Sánchez-Marín, FJ Pavón-Morón, FR de Fonseca… - Neuroscience …, 2022 - Elsevier
… R antagonist/inverse agonist SR141716A on voluntary alcohol … kg) and SR141716A (3 mg/kg)
reduce alcohol drinking in adult … /CB1 receptor dual ligands as a novel therapy for alcohol

The endocannabinoid system and alcohol dependence: Will cannabinoid receptor 2 agonism be more fruitful than cannabinoid receptor 1 antagonism?

A Oppong-Damoah, BM Gannon… - CNS & Neurological …, 2022 - ingentaconnect.com
… with the CB1 receptor antagonist/inverse agonist SR141716A … In an operant oral self-administration
model, treatment with … operant ethanol self administration in rats exposed to ethanol-…

The loss of NMDAR‐dependent LTD following cannabinoid selfadministration is restored by positive allosteric modulation of CB1 receptors

D Neuhofer, SM Spencer, VC Chioma… - Addiction …, 2020 - Wiley Online Library
… 0.28% to 0.56% ethanol, an equivalent concentration of … to the operant procedure, rats were
trained to self-administer … with rimonabant was accompanied by a decrease in sEPSC IEI (ie, …

Dissecting the role of CB1 and CB2 receptors in cannabinoid reward versus aversion using transgenic CB1-and CB2-knockout mice

X Li, BJ Hempel, HJ Yang, X Han, GH Bi… - European …, 2021 - Elsevier
… differential activation of cannabinoid receptors. Specifically, … are trained to make an operant
response to receive electrical … to Δ 9 -THC or SR141716A (a CB 1 R antagonist or inverse …

[HTML][HTML] Role of cannabinoid CB2 receptor in alcohol use disorders: From animal to human studies

MS García-Gutiérrez, F Navarrete, A Gasparyan… - International Journal of …, 2022 - mdpi.com
… the CB 1 r-antagonist SR141716A, marketed as rimonabant, … place preference (CPP),
ethanol-self administration), and the … alcohol consumption in the oral operant self-administration

Cannabinoid receptor type 1 antagonists alter aspects of risk/reward decision making independent of toluene-mediated effects

KM Braunscheidel, MP Okas, SB Floresco… - …, 2022 - Springer
… focused primarily on stimulants and alcohol. However, recent … SCM for two days prior to
operant training. Over the course of … engagement and/or reduced executive processing speeds. …

Oral cannabidiol does not alter alcohol seeking and selfadministration in baboons

CF Moore, CA Zamarripa, EM Weerts - Drug and alcohol dependence, 2023 - Elsevier
… and chronic administration of CBD could reduce alcohol seeking and self-… administration
of CBD on alcohol-seeking and alcohol self-administration during conditions of ongoing alcohol

Distinct antinociceptive and conditioned behavioral effects are produced by individual cannabinoids and a cannabis-derived mixture

T Morris, JA Cucinello-Ragland, TJ Marks… - Pharmacology …, 2024 - Elsevier
… that smoke inhalation of ethanol-extracted marijuana (a control … (TRPV1Rs) rather than
cannabinoid receptors. This was … of Δ 8 -THC and Δ 9 -THC on operant responding and tail-…