[HTML][HTML] Carbohydrate-based adjuvants

P Garcia-Vello, I Speciale, F Chiodo, A Molinaro… - Drug Discovery Today …, 2020 - Elsevier
Carbohydrate-based molecules are potent and safe adjuvants used alone or in combination.
They show advantages over alum such as reduced side effects and the activation of both …

Natural and synthetic carbohydrate-based vaccine adjuvants and their mechanisms of action

C Pifferi, R Fuentes, A Fernández-Tejada - Nature Reviews Chemistry, 2021 - nature.com
… molecular bases underlying the adjuvant activity of some of … of optimized adjuvants
and adjuvant combinations. … the development of carbohydrate-based adjuvants, including …

Carbohydrate-containing nanoparticles as vaccine adjuvants

X Zhang, Z Zhang, N Xia, Q Zhao - Expert Review of Vaccines, 2021 - Taylor & Francis
… Introduction: Adjuvants are essential to vaccines for … -based adjuvants have limited
capacity to induce cellular response. There are increasing needs for appropriate adjuvants with …

Immunobiology of carbohydrates: Implications for novel vaccine and adjuvant design against infectious diseases

G Stefanetti, F Borriello, B Richichi, I Zanoni… - Frontiers in Cellular and …, 2022 - frontiersin.org
… the only authorized adjuvant for carbohydrate-based vaccines. In this … or adjuvants, and we
review the use of currently available adjuvants to improve the efficacy of carbohydrate-based

Carbohydrate immune adjuvants in subunit vaccines

S Bashiri, P Koirala, I Toth, M Skwarczynski - Pharmaceutics, 2020 - mdpi.com
… for the development of new adjuvants. This review assesses … The role of carbohydrate-based
adjuvants/delivery systems … by APCs facilitated by carbohydrate-based adjuvants initiates …

Glycovaccinology: The design and engineering of carbohydrate-based vaccine components

SW Hulbert, P Desai, MC Jewett, MP DeLisa… - Biotechnology …, 2023 - Elsevier
… The second part of this review discusses the development of carbohydrates as vaccine
adjuvants to increase the immunogenicity of co-administered antigens. Here, we consider two …

[HTML][HTML] Recent advances and future perspectives on carbohydrate-based cancer vaccines and therapeutics

C Sorieul, F Papi, F Carboni, S Pecetta… - Pharmacology & …, 2022 - Elsevier
… studies, attempts of vaccination with carbohydrate-based candidates have proven unsuccessful,
… New strategies are thus deployed to enhance carbohydrate-based cancer vaccines. …

Carbohydrate-based macromolecular biomaterials

L Su, Y Feng, K Wei, X Xu, R Liu, G Chen - Chemical Reviews, 2021 - ACS Publications
… and related synthetic molecules, the carbohydrate-based building blocks discussed in
this … as immune adjuvants and antigens, which even fit the requirements of “carbohydrate-based

Immunology of carbohydrate-based vaccines

F Khatun, I Toth, RJ Stephenson - Advanced Drug Delivery Reviews, 2020 - Elsevier
… that contribute to the design of optimum antigens, synthesis of antigens and the studies of
antigen-antibody interactions, and as a result, several promising carbohydrate-based vaccine …

Carbohydrate conjugates in vaccine developments

S Lang, X Huang - Frontiers in Chemistry, 2020 - frontiersin.org
… carbohydrates as vaccine delivery carriers and adjuvants. We will discuss examples …
conjugates of antigens and carbohydrate-based delivery carrier or adjuvants. Vaccines that contain …