[HTML][HTML] Molecular pathogenesis and treatment of cavernous nerve injury-induced erectile dysfunction: a narrative review

G Song, P Hu, J Song, J Liu, Y Ruan - Frontiers in Physiology, 2022 - frontiersin.org
after CNI and induces the caspase-3-dependent apoptosis of … of CCSMCs by activating the
Akt/Bad/Bax/caspase-3 pathway… nitrergic and sympathetic innervation of the penis, followed

… nanofiber hydrogel delivery of Sonic hedgehog protein to the penis and cavernous nerve suppresses intrinsic and extrinsic apoptotic signaling mechanisms, which …

S Martin, DA Harrington, S Ohlander, SI Stupp… - … , Biology and Medicine, 2021 - Elsevier
… the neurons that innervate the penis, and TUNEL and caspase 3-… caspase 3-cleaved protein
in the corpora cavernosa afterinjury can suppress extrinsic caspase 8-dependent apoptotic

Low-intensity electrostimulation enhances neuroregeneration and improves erectile function in a rat model of cavernous nerve injury

M Sturny, S Karakus, R Fraga-Silva… - The journal of sexual …, 2022 - academic.oup.com
… loss of nitrergic nerve cells in the CN and diminish DPN nerve cells apoptosis following injury.
… and nNOS uncoupling thereby preserving neurogenically mediated nitrergic relaxation of …

169 COMP-4 Reduces Oxidative Stress Markers in the Rat Corpora Cavernosa and Media of the Penile Dorsal Artery

S Nguyen, K Arriaga Castellanos… - The Journal of …, 2020 - academic.oup.com
… from MPGs in a dosedependent fashion. MPGs cultured with … may prevent ED after BCNI
by protecting nitrergic nerves. … , caspase 3 cleaved was abundant from 1-9 days after injury, …

Rutin ameliorates nitrergic and endothelial dysfunction on vessels and corpora cavernosa of diabetic animals

R de Morais Campos, LMALL Lima, AG da Silva… - Research in Veterinary …, 2023 - Elsevier
dependent helicine arteries relaxation, increased arterial inflow and neuronal nitric oxide
(nitrergic) mediated … Rutin also decreased the caspase-3 and oxidative stress in diabetic nerves

An update on the current status and future prospects of erectile dysfunction following radical prostatectomy

H Asker, D Yilmaz‐Oral, CV Oztekin, S Gur - The Prostate, 2022 - Wiley Online Library
… and neural causes of ED and decrease patient dependence … and nitrergic relaxations
as well as apoptosis and fibrosis after … and oxidative stress by inhibiting the Akt/Bad/Bax/caspase-3

Fasudil attenuates glial cell-mediated neuroinflammation via ERK1/2 and AKT signaling pathways after optic nerve crush

W Huang, Q Lan, L Jiang, W Yan, F Tang… - Molecular Biology …, 2020 - Springer
… homeostasis and protecting retinal neurons [14]. … apoptosis [77]. Increasing evidence
suggested that the activations of caspase-3 and caspase-9 pathways were up-regulated after

[HTML][HTML] Fidgetin-like 2 negatively regulates axonal growth and can be targeted to promote functional nerve regeneration

L Baker, M Tar, AH Kramer, GA Villegas… - Jci Insight, 2021 - ncbi.nlm.nih.gov
… time for FL2 depletion following Cre-mediated excision of the … , we found the density of
nitrergic neurons in the caudal MPG … Peripheral nerve repair is largely dependent on Schwann …

siRNA mediated downregulation of RhoA expression reduces oxidative induced apoptosis in retinal ganglion cells

Q Liu, C Liu, B Lei - Current Molecular Medicine, 2024 - ingentaconnect.com
Caspase-3 dependent nitrergic neuronal apoptosis following … in major pelvic ganglion
mediates caspase-3 dependent nitrergic neuronal apoptosis following cavernous nerve injury. …

[HTML][HTML] Neuroprotection mediated by natural products and their chemical derivatives

F Fei, N Su, X Li, Z Fei - Neural Regeneration Research, 2020 - journals.lww.com
… contribute towards neuroprotection after neuronal damage. … own specific tissue-dependent
pharmacological effects. Many … and the activation of caspase-3 (Wang et al., 2016b; Table 1). …