Statins and peripheral neuropathy in diabetic and non-diabetic cases: a systematic review

M Daliri, TP Johnston, A Sahebkar - Journal of Pharmacy and …, 2023 - academic.oup.com
… RSV improved diabetic mice’s impaired NO-mediated nerve … , age-dependent vascular and
neural dysfunctions can be … in both caspase-3 activity and the level of pro-apoptotic GTPase …

Role of hydrogen sulfide in the male reproductive system

Y Song, C Mao, Q Zhong, R Zhang, D Jiang… - Frontiers in …, 2024 - frontiersin.org
… mostly depend on the relaxation of the cavernous smooth … neuronal excitation induces the
release of H2S to mediate … -adrenergic, non-cholinergic nitrergic (NANC) relaxation. Similarly, …

Traditional chinese medicine to prevent and treat diabetic erectile dysfunction

Y Feng, T Shi, Y Fu, B Lv - Frontiers in Pharmacology, 2022 - frontiersin.org
… In turn, ROS can affect nitrergic neurons and endothelial cells … adhesion molecules that
mediate vascular damage and … In a randomized control clinical trial, after 3 months of treatment …

Genome Editing to Abrogate Muscle Atrophy

T Yang, P Gokulnath, X Meng, G Li, J Xiao - Genome Editing in …, 2022 - Springer
… of the motor endplate depend on normal nerve innervation and … Caspase-3 is a major member
of the Fas apoptotic pathway … Recently, we reported a CRISPR-/Cas9-mediated miR-29b …

Metabonomic profiling of blood plasma from erectile dysfunction patients using 1H nuclear magnetic resonance spectroscopy

F Liu, A Ruze, W Liu, K Xiong… - Acta Biochimica et …, 2020 - academic.oup.com
After phase and baseline correction of all 1 H NMR spectra, the area of each metabolite …
mediates caspase-3 dependent nitrergic neuronal apoptosis following cavernous nerve injury

[HTML][HTML] Effects of bisphenol A exposure during pregnancy and lactation on hippocampal function in newborn rats

Y Wang, X Du, D Wang, J Wang… - International Journal of …, 2020 - ncbi.nlm.nih.gov
… and excessive apoptosis of these normal neurons may … in hippocampus of male offspring
after high concentration BPA … male offspring might be partly mediated by the regulation of RhoA …

Targeting ROCK2 isoform with its widely used inhibitors for faster post-stroke recovery

S Appunni, D Gupta, M Rubens, AK Singh… - Indian Journal of …, 2021 - amu.hal.science
… TJ, RhoA/ROCK activation in major pelvic ganglion mediates caspase-3 dependent nitrergic
neuronal apoptosis following cavernous nerve injury. Neural Regen Res, 12 (2017) 572. 10 …

Polyphenols targeting MAPK mediated oxidative stress and inflammation in rheumatoid arthritis

T Behl, T Upadhyay, S Singh, S Chigurupati… - Molecules, 2021 - mdpi.com
… were all suppressed in FLSs in humans after a dosage of 50 g for … Bax) irregularity and
caspase 3 and caspase 9 initiation [57]. … , TLR-dependent MAPK pathway activation mediates pro-…

Infliximab prevents dysfunction of the vas deferens by suppressing inflammation and oxidative stress in rats with chronic stress

TD Şahin, SS Gocmez, G Duruksu, Y Yazir, T Utkan - Life sciences, 2020 - Elsevier
… marked reduction in nerve-mediated contractile responses of … in stressed animals were not
dependent on any alterations in … the activation of caspase 3 (a good indicator of apoptosis) in …

A literature perspective on the pharmacological applications of yohimbine

NR Jabir, CK Firoz, TA Zughaibi, MA Alsaadi… - Annals of …, 2022 - Taylor & Francis
… The pharmacological activity of yohimbine is mediated by the … dose-dependent relaxant effect
on isolated rat corpus cavernosum [… significantly lowered the TNF-α, caspase 3/7, and IL-1β …