… B7-H3 as an immune checkpoint can affect the sensitivity of several cancer types including
colorectal cancer (CRC) to various anticancer drugs and targeted therapies [156]. The …

… polymerization, which is essential for cell cycle progression and cell division [9]. Furthermore,
a … , multiple approaches to tumor growth control are now available, and the process can be …

… Of note, CDK5 is not a canonical cell cycle regulator 46 , which suggests that its influence
on effector T cell functions is unrelated to cell cycle control. Further supporting this notion, …

… Therefore, to increase the effectiveness of targeting cell cycle control mechanisms by anticancer
… This could be used to guide better drug design, therapeutic combinations and patient …

… Aberrancy in cell cycle progression is … regulators of the cell cycle machinery rational
anticancer therapeutic targets. A growing body of evidence indicates that the cell cycle regulatory …

… a variety of cell cycle regulatory genes, such as anti-apoptotic factor Bcl-2, resulting in cell
cycle arrest … Therefore, miR-34 plays an important role in the regulation of cell proliferation and …

… diterpenoid, was discovered from the … cell cycle arrest by blocking microtubule depolymerization
and boosting microtubule polymerization, and PTX’s unusual structure and anticancer …

… the occurrence, development, progression … regulators have been identified as novel
anticancer drug targets. Both traditional medicine-related approaches and modern drug discovery …

… dysregulation is an established hallmark of cancer, and aberrant control of transcriptional …
regulating the cell cycle and transcription, CDK7 has been studied as an anticancer drug target…

… on the precise control of the cell cycle progression and guide anticancer drug development.
… signals involved in the cell cycle control. Moreover, non-proteolytic ubiquitination of the …