Ion channel dysfunction and fibrosis in atrial fibrillation: Two sides of the same coin
G Arabia, MG Bellicini, A Cersosimo… - Pacing and Clinical …, 2024 - Wiley Online Library
… In both cases atrial ectopic activity and electrical reentry circuits are increased, resulting
in cellular Ca2+ overload and fibrosis. Likewise, fibrosis can be directly due to profibrotic …
in cellular Ca2+ overload and fibrosis. Likewise, fibrosis can be directly due to profibrotic …
Obesity and atrial fibrillation: a narrative review from arrhythmogenic mechanisms to clinical significance
H Shu, J Cheng, N Li, Z Zhang, J Nie, Y Peng… - Cardiovascular …, 2023 - Springer
… that obese patients were more likely to develop AF, but others reported no significant correlation.
Obesity-… AF is caused by focal ectopic-triggering activity that is mainly caused by early …
Obesity-… AF is caused by focal ectopic-triggering activity that is mainly caused by early …
Establishment of Risk Model and Analysis of Immunoinfiltration Based on Mitophagy-Related Associated Genes in Atrial Fibrillation
W Sang, L Wang, X Yan, H Sun, Y Han… - Journal of …, 2023 - Taylor & Francis
… To explore the correlation between DEMRG expression and … activity. Ca 2+ handling-related
abnormalities form the underlying molecular basis for focal ectopic activity and atrial …
abnormalities form the underlying molecular basis for focal ectopic activity and atrial …
Gut microbiota metabolites connections with echocardiography atrial fibrillation characteristics in patients with coronary artery disease
I Melnychuk - 2024 - essuir.sumdu.edu.ua
… commonly increased in patients with atrial fibrillation, was correlated with TMA (r… activity,
which alters sarcoplasmic-reticulum Ca2+ release, exhibits ectopic activity, and shortened atrial …
which alters sarcoplasmic-reticulum Ca2+ release, exhibits ectopic activity, and shortened atrial …
Mechanisms and management of thyroid disease and atrial fibrillation: Impact of atrial electrical remodeling and cardiac fibrosis
A Takawale, M Aguilar, Y Bouchrit, R Hiram - Cells, 2022 - mdpi.com
… In fact, several large clinical studies found no residual correlation between clinical or
subclinical … Hyperthyroid patients have increased heart rates, more atrial ectopic activity (atrial …
subclinical … Hyperthyroid patients have increased heart rates, more atrial ectopic activity (atrial …
Pericardial Inflammatory Mediators That Can Drive Post-Operative Atrial Fibrillation in Cardiac Surgery Patients
AF Hassanabad, JF Deniset, PWM Fedak - Canadian Journal of Cardiology, 2023 - Elsevier
… linked AF onset with ectopy originating from the pulmonary veins in the left atrial tissue (60). …
To prospectively identify structural/molecular changes in atrial myocardium that correlate …
To prospectively identify structural/molecular changes in atrial myocardium that correlate …
The blinding period following ablation therapy for atrial fibrillation: proarrhythmic and antiarrhythmic pathophysiological mechanisms
Atrial fibrillation (AF) causes heart failure, ischemic strokes, and poor quality of life. The
number of patients with AF is estimated to increase to 18 million in Europe in 2050. …
number of patients with AF is estimated to increase to 18 million in Europe in 2050. …
Molecular basis of atrial fibrillation initiation and maintenance
K Beneke, CE Molina - Hearts, 2021 - mdpi.com
… ectopic activity initiates atrial arrhythmias in myocytes [17] and in whole hearts [18]. Thus, the
most prominent channels causing ectopic activity … term AF, which correlated with a switch to …
most prominent channels causing ectopic activity … term AF, which correlated with a switch to …
A review of the molecular mechanisms underlying cardiac fibrosis and atrial fibrillation
G Sygitowicz, A Maciejak-Jastrzębska… - Journal of Clinical …, 2021 - mdpi.com
… is correlated with the level of metalloproteinase inhibitors. Therefore, MMP activity increases
… in the myocardium, promoting fibrosis, and it correlates with the intensity of the inflammatory …
… in the myocardium, promoting fibrosis, and it correlates with the intensity of the inflammatory …
[HTML][HTML] MicroRNA-21 mediated cross-talk between cardiomyocytes and fibroblasts in patients with atrial fibrillation
K Pradhan, P Niehues, B Neupane… - Frontiers in …, 2023 - frontiersin.org
… of atrial fibrillation (AF). We have previously shown that circulating microRNA-21 (miR-21)
correlates with the extent of left atrial fibrosis in patients … of AF states that ectopic foci located in …
correlates with the extent of left atrial fibrosis in patients … of AF states that ectopic foci located in …