Pathophysiology of cardiovascular diseases: new insights into molecular mechanisms of atherosclerosis, arterial hypertension, and coronary artery disease

W Frąk, A Wojtasińska, W Lisińska, E Młynarska… - Biomedicines, 2022 - mdpi.com
… Additionally, microRNA (miR)-140-5p exaggerates AH and oxidative stress in mouse
models. Liu et al. established that downregulation of miR-140-5p reduced oxidative stress and …

Foam cells in atherosclerosis: novel insights into its origins, consequences, and molecular mechanisms

Y Gui, H Zheng, RY Cao - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
… , and molecular mechanisms of foam cells in atheroscleroticcell RNA sequencing has
been utilized to examine macrophage heterogeneity in multiple mouse models of atherosclerosis

Role of reactive oxygen species in atherosclerosis: Lessons from murine genetic models

A Negre-Salvayre, P Guerby, S Gayral… - Free Radical Biology …, 2020 - Elsevier
… from animal models … , cellular injury and inflammation in systemic hypertension and
cardiovascular diseases [106]. However, the molecular mechanisms linking XO to atherosclerosis

Role of lipid accumulation and inflammation in atherosclerosis: focus on molecular and cellular mechanisms

K Malekmohammad, EE Bezsonov… - Frontiers in …, 2021 - frontiersin.org
atherosclerosis is an inflammatory, cellular, and metabolic process (4, 8). So, elucidating
atherosclerosis … pathogenesis of atherosclerosis with more emphasis on cellular mechanisms. …

Mouse models of atherosclerosis and their suitability for the study of myocardial infarction

P Golforoush, DM Yellon, SM Davidson - Basic research in cardiology, 2020 - Springer
… In this review, we examine the main mouse models of atherosclerosis currently available,
their method … The aim is to identify which, if any, mouse model of atherosclerosis is suitable for …

Basic pathogenic mechanisms of atherosclerosis

HAH Alfarisi, ZBH Mohamed… - Egyptian Journal of Basic …, 2020 - Taylor & Francis
… (TMAO) which has been described in animal models and clinical trials as metabolite causing
… understand the molecular mechanisms that relate DNA methylation to atherosclerosis and …

[HTML][HTML] Small rodent models of atherosclerosis

Y Zhao, H Qu, Y Wang, W Xiao, Y Zhang… - Biomedicine & …, 2020 - Elsevier
Mouse models of atherosclerosis Currently, mice are the most extensively used animal
models in atherosclerosis … transgenic and knock-out murine models. These have provided a …

Atherosclerosis: Known and unknown

J Fan, T Watanabe - Pathology international, 2022 - Wiley Online Library
… In the past 30 years, the molecular mechanisms underlying … in humans to study the
mechanisms of plaque rupture, a … animal models that can develop coronary atherosclerosis

[HTML][HTML] The atherosclerosis-ameliorating effects and molecular mechanisms of BuYangHuanWu decoction

B Liu, Z Song, J Yu, P Li, Y Tang, J Ge - Biomedicine & Pharmacotherapy, 2020 - Elsevier
animal model was bulit and BuYangHuanWu decoction was determined to be effective in
treating atherosclerosis… the mechanism of BYHWD in the treatment of atherosclerosis by using …

Mechanism overview and target mining of atherosclerosis: Endothelial cell injury in atherosclerosis is regulated by glycolysis

R Wang, M Wang, J Ye, G Sun… - … journal of molecular …, 2021 - spandidos-publications.com
… At present, research on AS mainly uses genetically modified animal models, such as
ApoE−/− and db/db mice, and the findings cannot yet be translated into clinical application. …