Chaperonin TRiC/CCT participates in mammarenavirus multiplication in human cells via interaction with the viral Nucleoprotein

S Sakabe, H Witwit, R Khafaji, B Cubitt… - Journal of …, 2023 - Am Soc Microbiol
Rabies virus was reported to upregulate CCTγ (CCT3) in … complex on LCMV multiplication,
we infected A549 cells with … We hypothesized that the TRiC/CCT complex might contribute to …

[HTML][HTML] Function of host protein Staufen1 in rabies virus replication

G Liu, C Chen, R Xu, M Yang, Q Han, B Wang, Y Song… - Viruses, 2021 - mdpi.com
… cells increases viral replication in the host when infected by … STAU1 downregulation leads
to enhanced viral replication, we … , CCTγ and Prefoldin are important host factors for RABV …

[HTML][HTML] Rabies infection: an overview of lyssavirus-host protein interactions

F Zandi, F Goshadrou, A Meyfour… - Iranian biomedical …, 2021 - ncbi.nlm.nih.gov
… protein interactions, their contributions to rabies infection, and their … CCTγ to NBs, which
are factories for virus replication and this chaperonin facilitates viral transcription and replication, …

The TRiC/CCT chaperonin and its role in uncontrolled proliferation

DY Wang, K Kamuda, G Montoya, P Mesa - … and Molecular Chaperones in …, 2020 - Springer
… many essential cellular processes including cell cycle, cell division, DNA maintenance,
replication, repair and recombination, metabolism, transcription and translation, RNA processing, …

[HTML][HTML] TRiC/CCT complex, a binding partner of NS1 protein, supports the replication of Zika virus in both mammalians and mosquitoes

Y Wang, R Uraki, J Hwang, E Fikrig - Viruses, 2020 - mdpi.com
… TRiC/CCT complex as a chaperone during ZIKV replication. … on the production of infectious
particles, we infected KD and … TRiC/CCT complex contributes to ZIKV replication in mosquito …

The recruitment of TRiC chaperonin in rotavirus viroplasms correlates with virus replication

J Vetter, G Papa, K Tobler, JM Rodriguez, M Kley… - Mbio, 2024 - Am Soc Microbiol
… (TRiC), a cellular chaperonin responsible for the folding of at … virus progeny of RV-infected
cells treated with TRICi during … The contribution of NSP5 to the replication and packaging of …

[HTML][HTML] The role of molecular chaperones in virus infection and implications for understanding and treating COVID-19

L Paladino, AM Vitale, C Caruso Bavisotto… - Journal of clinical …, 2020 - mdpi.com
… surface, regulating signaling and cellular homeostasis [99]. … CoV-2 infectious cycle, and
to pinpoint chaperone-dependent … the data reported, and contributed to the writing; AMG …

[HTML][HTML] The TRiCky business of protein folding in health and disease

H Ghozlan, A Cox, D Nierenberg, S King… - Frontiers in Cell and …, 2022 - frontiersin.org
… essential process that when deregulated leads to diseases like … cellular folding machinery
that includes chaperone, co-… (M) when a cell separates the replicated chromosomes and …

Recruitment of TRiC chaperonin in rotavirus viroplasms directly associates with virus replication

J Vetter, G Papa, K Tobler, M Kley, M Myers… - bioRxiv, 2022 - biorxiv.org
… of lysates from rotavirus-infected cells expressing NSP5-BiolD2… the TRiC complex, a cellular
chaperonin responsible for the … The contribution of NSP5 also needs to be considered. Even …

[HTML][HTML] Looking at the Pathogenesis of the Rabies Lyssavirus Strain Pasteur Vaccins through a Prism of the Disorder-Based Bioinformatics

S Dhulipala, VN Uversky - Biomolecules, 2022 - mdpi.com
… the G-protein, form the sole ligand for the cellular receptor. Anti-… protein L9 during the initial
stages of RABV infection to … that made the greatest contribution to this interaction and that …