The mechanism of the cadmium-induced toxicity and cellular response in the liver

V Souza-Arroyo, JJ Fabián, L Bucio-Ortiz… - Toxicology, 2022 - Elsevier
… It is well established that cadmium competes with the essential metals to enter the organism
… Autophagy plays a crucial role in cellular homeostasis, as it contributes to energy generation …

An overview of molecular mechanisms in cadmium toxicity

D Đukić-Ćosić, K Baralić, D Javorac… - Current opinion in …, 2020 - Elsevier
Cell death resulting from Cd intoxication has been confirmed to occur through apoptosis
by … This toxic metal affects both extrinsic and intrinsic well-defined apoptotic regulatory …

[HTML][HTML] Effect of cadmium on essential metals and their impact on lipid metabolism in Saccharomyces cerevisiae

S Rajakumar, A Abhishek, GS Selvam… - Cell Stress and …, 2020 - Elsevier
… The ion transport system is essential for Cd influx, accumulation, and toxicity of the cells. …
vital metals like Zn and Ca and their transport and homeostatic mechanisms during Cd toxicity. …

[HTML][HTML] The effects of cadmium toxicity

G Genchi, MS Sinicropi, G Lauria, A Carocci… - International journal of …, 2020 - mdpi.com
… the effects of Cd exposure on human health, focusing on the cellular and molecular …
homeostasis of the essential metal ions Zn and Cu, the protection against Cd and other toxic metal

Cell organelles as targets of mammalian cadmium toxicity

WK Lee, F Thévenod - Archives of toxicology, 2020 - Springer
Cell organelles use lipid membranes to form complex tightly-… communication is crucial for
orchestrating correct cell behavior, … In this review, cadmium effects on organellar structure and …

Zinc as a countermeasure for cadmium toxicity

H Yu, J Zhen, J Leng, L Cai, H Ji… - Acta Pharmacologica …, 2021 - nature.com
… reduces cellular Cd uptake; therefore, metalhomeostasis are important for reducing
Cd toxicity. This review summarizes current knowledge related to the role of Zn and metal

Immunotoxicology of cadmium: Cells of the immune system as targets and effectors of cadmium toxicity

I Mirkov, AP Aleksandrov, M Ninkov, D Tucovic… - Food and Chemical …, 2021 - Elsevier
homeostatic reparative activities, stress this metal as an important health hazard. … mechanisms
responsible for cell/tissue injury induced by Cd is oxidative stress, even though this metal

Molecular mechanism of heavy metals (Lead, Chromium, Arsenic, Mercury, Nickel and Cadmium)-induced hepatotoxicity–A review

K Renu, R Chakraborty, H Myakala, R Koti… - Chemosphere, 2021 - Elsevier
… Another study on Cd-induced hepatotoxicity in rats suggested that cell membrane lesions
are caused due to lipid peroxidation and are also responsible for causing an alteration in the …

[HTML][HTML] Disruption of essential metal homeostasis in the brain by cadmium and high-fat diet

JC Mazzocco, R Jagadapillai, E Gozal, M Kong, Q Xu… - Toxicology reports, 2020 - Elsevier
… of cadmium and diet on essential metal homeostasis. Mice were exposed to cadmium and/or
… After 24 weeks brains were collected and then cadmium and essential metals measured by …

Glutathione: A key player in metal chelation, nutrient homeostasis, cell cycle regulation and the DNA damage response in cadmium-exposed Arabidopsis thaliana

S Hendrix, M Jozefczak, M Wójcik, J Deckers… - Plant Physiology and …, 2020 - Elsevier
… unknown and has never been evaluated in Cd-exposed plants. This study aimed … metal
chelation, nutrient homeostasis and cell cycle regulation in A. thaliana plants upon prolonged Cd