Nrf2 and oxidative stress

O Wada-Hiraike - Pathology, 2020 - Elsevier
… as a primary target for research involving neuroprotection, … Induction of cancer chemopreventive
enzymes by coffee is … novel target tissue of Nrf2 because it is highly susceptible to …

Role of Dietary Antioxidants in Chemoprevention of Nitrosamines-Induced Carcinogenesis

UDI Ejike, ML Liman - … of Oxidative Stress in Cancer: Therapeutic Aspects, 2022 - Springer
… The system makes a new cell to replace the destroyed ones … from getting to the targeted sites
and also support … in the brain, as such proffer neuroprotection to the brain. Several authors …

Plant natural products: Promising resources for cancer chemoprevention

L Ma, M Zhang, R Zhao, D Wang, Y Ma, L Ai - Molecules, 2021 - mdpi.com
… NF-B signaling pathway and its target genes Bcl-2 and Bax, … CA/MG as an effective
neuroprotective against oxaliplatin-induced … oxidative stress and inflammatory cytokines, improve …

Neuroprotection in Glaucoma: NAD+/NADH Redox State as a Potential Biomarker and Therapeutic Target

B Petriti, PA Williams, G Lascaratos, KY Chau… - Cells, 2021 - mdpi.com
… makes it an essential coenzyme for the health of the cell. … /RNA metabolism, and cellular
stress response. PARP–2 is the … , making Sirtuins a new potential target for glaucoma treatment. …

Targeting Nrf2 signaling pathway in cancer prevention and treatment: the role of cannabis compounds

A Rybarczyk, A Majchrzak-Celińska, V Krajka-Kuźniak - Antioxidants, 2023 - mdpi.com
… intricate interplay between cellular stress response, autophagy, … A growing body of evidence
suggests that the neuroprotective … (CBD) as a chemopreventive and anti-cancer agent. An …

Lignans from Eucommia ulmoides Oliver leaves exhibit neuroprotective effects via activation of the PI3K/Akt/GSK-3β/Nrf2 signaling pathways in H2O2-treated PC-12 …

R Han, Y Yu, K Zhao, J Wei, Y Hui, JM Gao - Phytomedicine, 2022 - Elsevier
… ulmoides leaves, including a new compound, (–)-7‑epi-… exhibited neuroprotective
activity in response to oxidative stress … , and the targets screened in the compound-target-pathway-…

[PDF][PDF] Targeting Nrf2 signaling pathway by quercetin in the prevention and treatment of neurological disorders: An overview and update on new developments

RF Obaid - researchgate.net
… the neuroprotective potential of Que on neurological disorders, with a particular emphasis
on the Nrf2 signaling pathway and oxidative stress. … elicited by chemopreventive agents that …

Neuroprotective effects of dietary plants and phytochemicals against radiation-induced cognitive and behavioral deficits: A comprehensive review of evidence and …

SV Raghu, AK Kudva, RG Krishnamurthy, J Mudgal… - Food & function, 2023 - pubs.rsc.org
… IR triggers cellular events that result in oxidative stress and damage to … goal arms (left and
right). Rodents prefer exploring a new arm over a known one, therefore, they switch the goal

The role of antioxidants in the interplay between oxidative stress and senescence

A Varesi, S Chirumbolo, LIM Campagnoli, E Pierella… - Antioxidants, 2022 - mdpi.com
… potential therapeutic targets to boost or delay cell senescence… on neurodegeneration by
direct neuroprotection against OS [… a cancer chemopreventive agent by promoting tumour cell

Healthy ageing and Mediterranean diet: A focus on hormetic phytochemicals

S Alì, S Davinelli, G Accardi, A Aiello, C Caruso… - Mechanisms of Ageing …, 2021 - Elsevier
… spend these extra years pursuing new careers, education, or … Cellular stress response
pathways are essential for ageing … , resveratrol did not exert its neuroprotective effect. This further …