[HTML][HTML] Programmed cell death in cerebellar Purkinje neurons

NS Erekat - Journal of integrative neuroscience, 2022 - imrpress.com
… Then, PN death in rodent mutants, namely shaker mutant rat … of apoptosis and autophagy
in lurcher mutant rat and shaker … for the molecular heterogeneity of Purkinje cells [162]. The …

Slc9a6 mutation causes Purkinje cell loss and ataxia in the shaker rat

KP Figueroa, CJ Anderson, S Paul… - Human Molecular …, 2023 - academic.oup.com
… wt and shaker rats, we performed western blotting of cerebellarmutation leads to neuronal
degeneration through apoptosis (43), which is the mechanism for PCs death in the shaker rat (…

Patterns of apoptosis and autophagy activation after hydroxyurea exposure in the rat cerebellar external granular layer: An immunoperoxidase and ultrastructural …

V Molina, L Rodríguez-Vázquez, J Martí - Neurotoxicity Research, 2020 - Springer
… number of Purkinje cells and deep cerebellar nuclei neurons, … exposure to HU promotes, in
addition to apoptotic cell death, … previously reported in the shaker mutant rats (Erekat 2018), …

Cerebellar Biochemistry/Pharmacology

T Seki - … for Cerebellar Ataxias: From Cellular Models to Human …, 2023 - Springer
… layer, Purkinje cell (PC) layer, and granule cell layer (Fig. 1). … PC degeneration in shaker
mutant rats (Tolbert and Clark … the apoptosis of PCs during the postnatal development of the …

[HTML][HTML] TGF-β1 provides neuroprotection via inhibition of microglial activation in 3-acetylpyridine-induced cerebellar ataxia model rats

BB Cao, XX Zhang, CY Du, Z Liu, YH Qiu… - Frontiers in …, 2020 - frontiersin.org
shaker. The supernatant containing the detached microglial … cell bodies and terminals of
Purkinje cells in the cerebellum. … loss and apoptosis in the brain stem and cerebellum of CA rats. …

Apoptosis, Autophagy, and Unfolded Protein Response and Cerebellar Development

AB Behrrooz, M Rahmati, Z Talaie, N Ashtari… - … of the Cerebellum from …, 2023 - Springer
Purkinje cells (PCs) and cerebellar nuclei (CN) neurons are some … In humans, it has been
shown that cerebellar PC deathShaker mutant rats have an X-linked recessive mutation that …

[HTML][HTML] Infant and adult SCA13 mutations differentially affect Purkinje cell excitability, maturation, and viability in vivo

JY Hsieh, BN Ulrich, FA Issa, MA Lin, B Brown… - Elife, 2020 - elifesciences.org
death of iR4H-expressing Purkinje cells in zebrafish during … survival of Purkinje cells during
cerebellar development in … membranes of living and early apoptotic cells. It intercalates into …

Histo-morphological evaluations of the cerebellum in dihydrocodeine-treated rat models

A Thomas, G Akunna, GB Ojo… - Journal of Current …, 2021 - journals.unizik.edu.ng
… Programmed cell death in the cerebellum has been known to … of rats had normal Purkinje
cells and histological cerebellarcells in the molecular deposit of the cerebellum with huge …

Dysfunction of cerebellar microglia in ataxia‐telangiectasia

H Levi, E Bar, S Cohen‐Adiv, S Sweitat, S Kanner… - Glia, 2022 - Wiley Online Library
… role in the loss of cerebellar Purkinje cells in AT. Following injury … room temperature on an
orbital shaker covered in aluminum foil… suggestive of apoptosis; however, since these cells are …

[HTML][HTML] Acute cerebellar inflammation and related ataxia: mechanisms and pathophysiology

MSA Parvez, G Ohtsuki - Brain sciences, 2022 - mdpi.com
… of the cerebellar Purkinje cells and hypoexcitability of the … endothelial injury and apoptosis
of parenchymal cells, which … motor incoordination by peripheral inflammation in rats [228]. It …