[HTML][HTML] Cerebral tissue pO2 response to treadmill exercise in awake mice

M Moeini, C Cloutier-Tremblay, X Lu, A Kakkar… - Scientific Reports, 2020 - nature.com
cerebral tissue pO 2 at rest and during neural stimulation has … -week-old male C57BL/6J
mice that maximal oxygen uptake (… the oxygen supply and consumption is maintained from L1 to …

The oxygen initial dip in the brain of anesthetized and awake mice

AK Aydin, C Verdier, E Chaigneau… - Proceedings of the …, 2022 - National Acad Sciences
… ISIO and BOLD fMRI in response to natural sensory stimulation. … Neural responses were
maintained and systematically … Adult mice (3 to 12 mo old, 20 to 35 g, both males and females, …

Optical measurement of microvascular oxygenation and blood flow responses in awake mouse cortex during functional activation

İ Şencan, T Esipova, K Kılıç, B Li… - Journal of Cerebral …, 2022 - journals.sagepub.com
… of stimulus-induced intravascular partial pressure of O 2 (pO2… We used 10 mice in this
study (C57BL/6, 3–5 months old, … whether this conserved behavior of the pO 2 response can …

Hemodynamic and oxygen-metabolic responses of the awake mouse brain to hypercapnia revealed by multi-parametric photoacoustic microscopy

R Cao, A Tran, J Li, Z Xu, N Sun… - … Cerebral Blood Flow & …, 2021 - journals.sagepub.com
… used stimulus for measuring cerebrovascular reactivity (CVR), … The water was kept at 37 C
throughout the imaging period. … the ROI, and W is the tissue weight estimated by assuming an …

[HTML][HTML] Cerebrovascular blood flow design and regulation; vulnerability in aging brain

DF Wilson, FM Matschinsky - Frontiers in Physiology, 2020 - frontiersin.org
… the metabolic and vascular responses in brain and how they … consumption observed with
somatosensory stimulation but is … has retained the mechanism common to other tissues with …

[PDF][PDF] The effect of age on neuro-vascular reactivity in mice

Z Fan - 2021 - edoc.ub.uni-muenchen.de
… forepaw stimulation, deeper regions in the rat brain respond … was maintained with 2%
isoflurane mixed with 30% oxygen … the young mice and 1 year-old mice in any of the stimulation. …

Voluntary exercise increases brain tissue oxygenation and spatially homogenizes oxygen delivery in a mouse model of Alzheimer's disease

X Lu, M Moeini, B Li, O de Montgolfier, Y Lu… - … of aging, 2020 - Elsevier
… cortex of awake transgenic AD mice. Our results show that … dose-response relationship of
exercise on the brain. Overall, … an important means for preserving neurovascular coupling and …

Hypertension accelerates cerebral tissue PO2 disruption in Alzheimer's disease

X Lu, M Moeini, B Li, E Thorin, F Lesage - Neuroscience Letters, 2020 - Elsevier
… This study measured stimulus-evoked brain tissue oxygenation changes in a mouse model
of … role of hypertension on tissue oxygen delivery and response to stimulation in the APP-PS1 …

[HTML][HTML] Behavioral and neural activity-dependent recanalization of plugged capillaries in the brain of adult and aged mice

P Reeson, B Schager, M Van Sprengel… - Frontiers in Cellular …, 2022 - frontiersin.org
… Further, we show that stimulating brain activity through … a surgical plate with body temperature
maintained at 37C. A hole … Note the rapid and sustained increase in response amplitude …

[HTML][HTML] Enhanced cerebral blood volume under normobaric hyperoxia in the J20-hAPP mouse model of Alzheimer's disease

O Shabir, P Sharp, MA Rebollar, L Boorman… - Scientific Reports, 2020 - nature.com
responses at an earlier age, around 6 m, in the J20-mouse … in our J20-hAPP mice to
stimulations, the haemodynamics … that neurovascular function is preserved in these mice. A key …