Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's disease

NJ Ashton, AL Benedet, TA Pascoal, TK Karikari… - …, 2022 - thelancet.com
Background Phosphorylated tau (p-tau) epitopes in cerebrospinal fluid (CSF) are accurate
biomarkers for a pathological and clinical diagnosis of Alzheimer's disease (AD) and are seen …

Biomarkers for central nervous system injury in cerebrospinal fluid are elevated in COVID‐19 and associated with neurological symptoms and disease severity

J Virhammar, A Nääs, D Fällmar… - European journal of …, 2021 - Wiley Online Library
… studies have investigated the cerebrospinal fluid (CSF) in … There are few reports on results
from CSF analysis in patients … -19, but rather to select patients with whom we had optimal …

Cryo-electron microscopy of extracellular vesicles from cerebrospinal fluid

A Emelyanov, T Shtam, R Kamyshinsky, L Garaeva… - PloS one, 2020 - journals.plos.org
… taken for nanoparticle tracking analysis (NTA) and flow cytometry analysis. To prepare the
… in 40 μL of PBS, rapidly frozen in liquid nitrogen, aliquoted and stored at -80C until analysis. …

Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid

A Drieu, S Du, SE Storck, J Rustenhoven… - Nature, 2022 - nature.com
… content itself, we performed a proteomics analysis of CSF sampled from PBM-depleted …
analysis was conducted, and an elbow plot was used to select the first 30 PCs for tSNE analysis

Methylation data processing protocol and comparison of blood and cerebral spinal fluid following aneurysmal subarachnoid hemorrhage

AI Arockiaraj, D Liu, JR Shaffer, TA Koleck… - Frontiers in …, 2020 - frontiersin.org
… In conclusion, the correlation analysis and QC pipelines … event we employed surrogate
variable analysis (SVA) to perform … of any particular phenotype-specific analyses, we generated a …

Predicting post-operative cerebrospinal fluid (CSF) leak following endoscopic transnasal pituitary and anterior skull base surgery: a multivariate analysis

CJ Hannan, H Almhanedi, R Al-Mahfoudh… - Acta …, 2020 - Springer
analysis was performed using the Chi-squared and Fisher’s exact tests, as appropriate. A
logistic regression model was constructed for multivariate analysis… On multivariate analysis, a …

Gray matter, white matter and cerebrospinal fluid abnormalities in Parkinson's disease: A voxel-based morphometry study

CO Nyatega, L Qiang, MJ Adamu… - Frontiers in Psychiatry, 2022 - frontiersin.org
… We decided to use all of the available data for further analysis by combining all patients in
one … The 100 voxel extent threshold was chosen and finally we used xjview (45) toolbox for …

Cerebrospinal fluid regulates skull bone marrow niches via direct access through dural channels

JA Mazzitelli, LCD Smyth, KA Cross, T Dykstra… - Nature …, 2022 - nature.com
It remains unclear how immune cells from skull bone marrow niches are recruited to the
meninges. Here we report that cerebrospinal fluid (CSF) accesses skull bone marrow via dura–…

Single-dose liposomal amphotericin B treatment for cryptococcal meningitis

JN Jarvis, DS Lawrence, DB Meya… - … England Journal of …, 2022 - Mass Medical Soc
… Fungal clearance from cerebrospinal fluid was −0.40 log 10 colony-forming units (CFU)
per milliliter per day in the liposomal amphotericin B group and −0.42 log 10 CFU per milliliter …

Differences between plasma and cerebrospinal fluid glial fibrillary acidic protein levels across the Alzheimer disease continuum

AL Benedet, M Milà-Alomà, A Vrillon, NJ Ashton… - JAMA …, 2021 - jamanetwork.com
… -analysis demonstrated that GFAP levels were consistently altered in the cerebrospinal fluid
… Our results point to plasma GFAP as a possible biomarker specific for Aβ pathology. First, …