[HTML][HTML] Head and neck squamous cell carcinoma

DE Johnson, B Burtness, CR Leemans… - Nature reviews Disease …, 2020 - nature.com
… The EGFR monoclonal antibody cetuximab is generally used in combination with radiation
in HPV-negative HNSCC where comorbidities prevent the use of cytotoxic chemotherapy. …

[HTML][HTML] Effectiveness of cetuximab as preemptive postsurgical therapy for oral squamous cell carcinoma patients with major risk: a single‐center retrospective cohort …

C Fukumoto, Y Sawatani, R Shiraishi, M Zama… - Investigational New …, 2021 - Springer
… However, Palmer et al. found that radiotherapy + cetuximab was well tolerated and resulted
… with radiotherapy + cetuximab for cutaneous squamous cell cancer of the head and neck in …

[HTML][HTML] … -EGFR antibody tomuzotuximab against cetuximab in patients with recurrent and/or metastatic squamous cell cancer of the head and neck–the RESGEX study

K Klinghammer, J Fayette, A Kawecki, A Dietz… - ESMO open, 2021 - Elsevier
Background The aim of the RESGEX study was to compare the efficacy and safety of the anti-epidermal
growth factor receptor (anti-EGFR) antibody tomuzotuximab against cetuximab

[HTML][HTML] Current trends and future prospects of molecular targeted therapy in head and neck squamous cell carcinoma

N Kitamura, S Sento, Y Yoshizawa, E Sasabe… - International journal of …, 2020 - mdpi.com
… Phase II study of the combination of cetuximab and weekly paclitaxel in the first-line treatment
of patients with recurrent and/or metastatic squamous cell carcinoma of head and neck. …

Early response dynamics predict treatment failure in patients with recurrent and/or metastatic head and neck squamous cell carcinoma treated with cetuximab and …

DJ Glazar, M Johnson, J Farinhas, CE Steuer, NF Saba… - Oral Oncology, 2022 - Elsevier
… Recurrent and/or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) is
currently an incurable disease. To improve treatment strategies, combinations of cetuximab plus …

Weekly cetuximab and paclitaxel for recurrent or metastatic head and neck squamous cell carcinoma

C Fushimi, D Baba, T Masubuchi, M Yamazaki, Y Kitani… - in vivo, 2020 - iv.iiarjournals.org
… with weekly cetuximab and … cetuximab previously had shorter PFS and OS than those who
had not. Conclusion: Cmab-PTX may be considered as a treatment option in head and neck

Combined taxane, platinum, and cetuximab as a first‐line treatment for recurrent/metastatic head and neck squamous cell carcinoma: Retrospective study

Y Liu, L Xue, Z Xia, Q Zhang, Y Guo - Head & Neck, 2022 - Wiley Online Library
… There is limited evidence supporting the use of taxane‐based chemotherapy combined
with cetuximab to treat recurrent/metastatic head and neck squamous cell carcinoma (R/M …

… cetuximab and radiotherapy for low risk HPV associated oropharyngeal cancer and locoregionally advanced squamous cell carcinoma of the head and neck in …

PL Swiecicki, P Li, E Bellile, C Stucken, K Malloy… - Head & …, 2020 - Wiley Online Library
Cetuximab represents a potential option for those ineligible for cisplatin or, until recently,
an … carcinoma (OPSCC). Our objective was to define the toxicity and efficacy of cetuximab-…

lncRNA PVT1 promotes cetuximab resistance of head and neck squamous cell carcinoma cells by inhibiting miR‐124‐3p

S Yang, ZJ Yuan, YH Zhu, X Chen, W Wang - Head & Neck, 2021 - Wiley Online Library
Cetuximab has been widely used in the clinical treatment of head and neck squamous
cell carcinoma (… 1 (lncRNA PVT1) is correlated with cetuximab resistance remains unclear. …

… phase 2 study of temsirolimus and cetuximab versus temsirolimus alone in recurrent/metastatic, cetuximab‐resistant head and neck cancer: The MAESTRO study

TY Seiwert, S Kochanny, K Wood, FP Worden… - Cancer, 2020 - Wiley Online Library
head and neck squamous cell carcinomas (HNSCCs) express epidermal growth factor receptor
(EGFR), and its presence is associated with poor outcomes. Cetuximab, … -dependent cell-…