… –human co-clinical trials demonstrate superior anti-tumour effects of buparlisib (BKM120) and cetuximab combination in squamous cell carcinoma of head and neck

HR Kim, HN Kang, MR Yun, KY Ju, JW Choi… - … journal of cancer, 2020 - nature.com
… (buparlisib/cetuximab), buparlisib monotherapy and cetuximab monotherapy is necessary. …
cetuximab monotherapy in head and neck cancer patients. In general, the RR of cetuximab

… , phase 4 study in patients with first‐line recurrent and/or metastatic squamous cell carcinoma of the head and neck treated with cetuximab and platinum‐based …

J Guigay, E Chamorey, G Lefebvre, M Rotarski… - Cancer …, 2022 - Wiley Online Library
… The primary aim of this study was to assess the relative dose intensity of cetuximab in
patients with R/M SCCHN treated with first-line cetuximab according to the EXTREME regimen. …

Consistent administration of cetuximab is associated with favorable outcomes in recurrent/metastatic head and neck squamous cell carcinoma in an endemic …

HC Wang, PL Liu, PC Lo, YT Chang, LP Chan, TJ Yeh… - PeerJ, 2020 - peerj.com
… This study aimed to analyze the clinical outcomes associated with patients with recurrent/metastatic
head and neck squamous cell carcinoma (RM HNSCC) who received cetuximab-…

Functional profiling of head and Neck/Esophageal squamous cell carcinoma to predict cetuximab response

SR Selvan, JA Brichetti, DB Thurber… - Cancer Biotherapy & …, 2021 - liebertpub.com
… Background: Cetuximab, an epidermal growth factor receptor (EGFR)-targeting … for squamous
cell carcinoma (SCC) of head and neck/esophagus. However, in clinical trials, cetuximab

Quality of Life of Patients with Head and Neck Cancer Receiving Cetuximab, Fluorouracil, Cisplatin Comparing to Cetuximab, Fluorouracil, Cisplatin, and Docetaxel …

U Goerling, T Gauler, A Dietz, V Grünwald… - Oncology Research …, 2022 - karger.com
… of cetuximab (C), 5-flourouracil, and cisplatin with the same regimen adding docetaxel (D) in
recurrent/metastatic head and neck cancersquamous cell carcinoma of the head and neck (…

Quality of life analysis of patients treated with cetuximab or cisplatin for locoregionally advanced squamous cell carcinoma of head and neck in the United States

H Aggarwal, RS Punekar, L Li, GC Carter… - Health and Quality of …, 2020 - Springer
… and neck cancers, with 64,690 new cases and … head and neck cancers are squamous cell
carcinomas that arise in the squamous cells lining the mucosal surfaces inside the head and …

906P Simlukafusp α and cetuximab combination in patients with recurrent, unresectable or metastatic squamous cell carcinoma of the head and neck

AR Hansen, CA Gomez-Roca, MP Lolkema… - Annals of …, 2021 - annalsofoncology.org
… of immune effector NK and CD8 T cells but not regulatory T cells. This phase I study evaluated
cetuximab (CET) by SIM in patients (pts) with head and neck squamous cell carcinoma (…

Palbociclib and cetuximab in cetuximab-resistant human papillomavirus-related oropharynx squamous-cell carcinoma: A multicenter phase 2 trial

P Oppelt, JC Ley, F Worden, K Palka, R Maggiore, J Liu… - Oral Oncology, 2021 - Elsevier
… in cetuximab-resistant human papillomavirus (HPV)-unrelated head and neck squamous-cell
carcinoma (… In this study, we aimed to determine the proportion of patients with cetuximab-…

Adverse events secondary to cetuximab therapy in head & neck cancer therapy and risk factors for serious outcomes

D Stanbouly, E Philipone, AB Morlandt, A Kaleem… - Oral oncology, 2022 - Elsevier
… to cetuximab therapy for head and neck cancer and … events from cetuximab therapy in head
and neck cancer treatment, of … The strongest risk factor for a serious outcome was cetuximab

[HTML][HTML] Therapeutic approaches for the treatment of head and neck squamous cell carcinoma–An update on clinical trials

B Goel, AK Tiwari, RK Pandey, AP Singh, S Kumar… - Translational …, 2022 - Elsevier
… Median OS was reported to be 9.7 months in palbociclib plus cetuximab group and 7.8
months in cetuximab group, showing a prolongation of median OS in combination group …