Challenges and opportunities for the next generation of cardiovascular tissue engineering

S Cho, DE Discher, KW Leong, G Vunjak-Novakovic… - Nature …, 2022 - nature.com
… in cardiac tissue engineering, with a focus on in vitro models of the human heart. Looking
ahead, we discuss major challenges and … of engineered cardiac tissues as models of cardiac

[HTML][HTML] 3D bioprinting in cardiac tissue engineering

Z Wang, L Wang, T Li, S Liu, B Guo, W Huang, Y Wu - Theranostics, 2021 - ncbi.nlm.nih.gov
… Finally, we discuss several crucial challenges and … major challenges of current 3DBP
strategies, describe future trends, and provide our perspective on the potential of bioprinted cardiac

3D bioprinting of cardiac tissue: Current challenges and perspectives

B Kato, G Wisser, DK Agrawal, T Wood… - Journal of Materials …, 2021 - Springer
… Alginate is a naturally occurring polysaccharide commonly used to model cardiac tissue or
for cardiac tissue engineering. The ability to be combined with diverse biomaterials improves …

Biomaterializing the promise of cardiac tissue engineering

JE Pomeroy, A Helfer, N Bursac - Biotechnology advances, 2020 - Elsevier
… In this review, we describe recent progress in the field of cardiac tissue engineering with
particular emphasis on use of biomaterials for therapeutic tissue design and delivery. …

Electrospun scaffolds and induced pluripotent stem cell-derived cardiomyocytes for cardiac tissue engineering applications

TC Suh, AY Amanah, JM Gluck - Bioengineering, 2020 - mdpi.com
… The level of scale-up required to generate this volume and density of cells has posed
challenges for the development of engineered cardiac tissue [6]. The use of induced pluripotent …

Natural biomaterials for cardiac tissue engineering: a highly biocompatible solution

QA Majid, ATR Fricker, DA Gregory… - … in cardiovascular …, 2020 - frontiersin.org
… many challenges to overcome before in vitro generated cardiac implants… One of these
challenges is associated with a difficulty of … Other challenges are related to vascularization which …

Tunable human myocardium derived decellularized extracellular matrix for 3D bioprinting and cardiac tissue engineering

G Basara, SG Ozcebe, BW Ellis, P Zorlutuna - Gels, 2021 - mdpi.com
… The generation of 3D tissue constructs with multiple cell types and matching mechanical
properties remains a challenge in cardiac tissue engineering. Recently, 3D bioprinting has …

Next generation of heart regenerative therapies: progress and promise of cardiac tissue engineering

MF Tenreiro, AF Louro, PM Alves… - NPJ Regenerative …, 2021 - nature.com
cardiac tissue in vitro is still challenging. Despite this, it is becoming possible to robustly
engineer miniaturized tissue versions … This review highlights recent progress in cardiac stem cell …

Fabrication, applications and challenges of natural biomaterials in tissue engineering

S Ullah, X Chen - Applied Materials Today, 2020 - Elsevier
… In this review, we will explore the fabrication, challenges and applications of natural
biomaterials for various tissues engineering issues, including polymer selection, fabrication …

Supramolecular adhesive hydrogels for tissue engineering applications

Y Zhao, S Song, X Ren, J Zhang, Q Lin… - Chemical …, 2022 - ACS Publications
… With the aid of a simulation-guided strategy, this self-adaptive epicardial patch has the
potential to deal with the human clinical challenges in cardiac tissue engineering. …