… , Acinetobacter baumannii, Pseudomonas aeruginosa, and … baumannii infections, there is
mounting pressure to find new … While A.baumannii remains a major public health challenge …

… identification in less than 40% of patients with clinically diagnosed IVACs [12]. This has
traditionally made challenging … ; (b) to appropriately place novel antimicrobial agents in lack of …

… To develop new efficacious antimicrobial agents, it is necessary to know the pathways …
mechanisms of virulence and antibacterial resistance is crucial to identify new biological targets. …

… baumannii, with the objective of identifying the most … that effectively escape the effects
of antibacterial drugs [16]. … such as Pseudomonas aeruginosa, Acinetobacter baumannii, …

… Multidrug resistance to antibiotics is a challenging global … , Pseudomonas aeruginosa,
Acinetobacter baumannii) present … initial attributes of an antibacterial agent effective against Gram-…

… Bacterial biofilms still remain a challenge to the healthcare system due to their resilience
against antimicrobial agents and immune system. Moreover, mechanisms involved in biofilm …

… It is intrinsically resistant to many antimicrobial agents and additional acquired … to
ceftolozane-tazobactam has been identified in P. … aeruginosa, in challenging clinical situations …

… baumannii poses a significant treatment challenge. This … infections by pathogens like
Pseudomonas aeruginosa and A. … last-line antimicrobial agents poses a considerable challenge, …

… preferred regimens have not been identified, we advocate for … CR Enterobacterales and
Pseudomonas aeruginosa do not … , treatment of CRAB infections remains a major challenge for …

… baumannii, Pseudomonas aeruginosa and Enterobacter spp.… a serious challenge for
clinicians. In another hand, soft tissue … drugs and traditional antibiotics has been identified as a …