Drugs with new lease of life as quorum sensing inhibitors: for combating MDR Acinetobacter baumannii infections

…, HK Abd El Latif, MA Shaldam, A El-Ganiny - … & Infectious Diseases, 2020 - Springer
infections has stimulated research to identify QS inhibitors (QSIs) to defeat microbes. In this
study, four FDA-approved drugs (… used in this study: Pseudomonas aeruginosa O1 (PAO1) as …

Treatment of Acinetobacter baumannii severe infections

R Reina, C León-Moya, J Garnacho-Montero - Medicina Intensiva (English …, 2022 - Elsevier
… of colistin base has been a challenge for defining the optimum dose of … Pseudomonas
aeruginosa and Acinetobacter baumannii – including strains resistant to carbapenems. This new

[HTML][HTML] Prospective role of cefiderocol in the management of carbapenem-resistant Acinetobacter baumannii infections: review of the evidence

M Kollef, H Dupont, DE Greenberg, P Viale… - … of Antimicrobial Agents, 2023 - Elsevier
baumannii and Pseudomonas aeruginosa. Cefiderocol is … cases in patients with underlying
health problems. To date, the … A recent analysis identified effluent flow rate during CRRT as …

Acinetobacter baumannii: an evolving and cunning opponent

J Shi, J Cheng, S Liu, Y Zhu, M Zhu - Frontiers in Microbiology, 2024 - frontiersin.org
… , which makes treating them challenging. Through carbapenem … Quinolones are synthetic
antimicrobial drugs with the basic … RND superfamily proteins have been identified in two efflux …

Cost analysis of new antibiotics to treat multidrug-resistant bacterial infections: mind the gap

D Yahav, D Shepshelovich, N Tau - Infectious Diseases and Therapy, 2021 - Springer
antibiotic drugs compared to older antibiotics for the … or MDR Pseudomonas aeruginosa
was doubled with new drugs; … In addition to the medical challenges posed by these infections, …

Multidrug-resistant gram-negative organisms: a review of recently approved antibiotics and novel pipeline agents

A Provenzani, AR Hospodar, AL Meyer… - International Journal of …, 2020 - Springer
… Unfortunately, challenges with new antibiotic discovery and … antimicrobial with activity against
Acinetobacter baumannii, … Ftortiazinon is a new antimicrobial agent administered as 300 …

[HTML][HTML] … agents against carbapenem-non-susceptible Pseudomonas aeruginosa and Acinetobacter baumannii isolates associated from bloodstream infection in …

PY Liu, WC Ko, WS Lee, PL Lu, YH Chen… - … and Infection, 2022 - Elsevier
… development of new antimicrobial agents is essential. Novel … Species identification was
performed at each site and … challenge to global health. There is a great need to optimize …

Clinical perspective of antimicrobial resistance in bacteria

Y Zhu, WE Huang, Q Yang - Infection and drug resistance, 2022 - Taylor & Francis
… most important antibacterial agents for multidrug-resistant infections of gram-… Acinetobacter
baumannii and Pseudomonas aeruginosa may gradually turn into a major clinical challenge

Drug‑resistant Acinetobacter baumannii: From molecular mechanisms to potential therapeutics

HJ Wu, ZG Xiao, XJ Lv, HT Huang… - Experimental and …, 2023 - spandidos-publications.com
… , Acinetobacter baumannii, Pseudomonas aeruginosa and … Acinetobacter baumannii is now
causing serious problems in … antibacterial agents, reducing the accumulation of antibiotics

Navigating Available Treatment Options for Carbapenem-Resistant Acinetobacter baumannii-calcoaceticus Complex Infections

RK Shields, DL Paterson… - Clinical Infectious …, 2023 - academic.oup.com
… highlight a broader challenge of identifying effective treatment for CRAB … antibacterial agents
for multiple drug-resistant and extensively drug-resistant Acinetobacter baumannii infections