Acute highaltitude hypoxia exposure causes neurological deficits via formaldehyde accumulation

X Wang, H Sun, L Cui, X Wang, C Ren… - CNS Neuroscience & …, 2022 - Wiley Online Library
… of the hypoxic group were cultured in 1% O 2 15 (calculated with … ) The levels of iron in the
cerebrum detected with quantitative … the changes of the brain tissue and neurons after CoQ10 …

[HTML][HTML] … apoptosis and promoted neuronal regeneration and memory/cognitive functions in the hippocampus induced by exposure to a chronic high-altitude hypoxia …

C Chen, B Li, H Chen, Y Qin, J Cheng, B He… - Neurochemical …, 2022 - Springer
… Behavioral alterations were assessed with the Morris water … Furthermore, we utilized
quantitative susceptibility mapping (QSM), … by which brain iron contents were changed by HAH, we …

[HTML][HTML] Effects of long-term exposure to high altitude hypoxia on cognitive function and its mechanism: a narrative review

Y Li, Y Wang - Brain sciences, 2022 - mdpi.com
… (VBM) analysis and measurement were performed, so as to … high altitude hypoxia exposure
leads to structural changes in … the regularity of quantitative and qualitative changes in the …

Differential effects of high-altitude exposure on markers of oxidative stress, antioxidant capacity, and iron profiles

CL Rytz, M Pun, JA Mawhinney… - … Journal of …, 2022 - journals.physiology.org
Changes in oxidative stress are also noted during hypoxic … , we determined that individuals
repeatedly exposed to … significant changes in blood plasma levels of oxidative stress levels, …

[HTML][HTML] High-altitude hypoxia exposure induces iron overload and ferroptosis in adipose tissue

Y Zhang, J Fang, Y Dong, H Ding, Q Cheng, H Liu… - Antioxidants, 2022 - mdpi.com
… As reported, chronic HA hypoxia causes brain iron … relevant proteins were measured. Overall,
this study revealed that HA … We investigated the changes in iron levels by iron staining and …

[HTML][HTML] The human brain in a high altitude natural environment: A review

X Zhang, J Zhang - Frontiers in Human Neuroscience, 2022 - frontiersin.org
… In a recent study, brain iron levels were found to increase in … (fMRI) is used to measure
changes in blood dynamics caused by … High altitude hypoxia is a natural model, and its damaged …

[HTML][HTML] Hypoxia and inflammation: insights from high-altitude physiology

K Pham, K Parikh, EC Heinrich - Frontiers in physiology, 2021 - frontiersin.org
… of iron sequestration is that this also limits iron availability for … changes may occur within or
across generations of exposurelevels after a couple days then exceeds baseline levels by 5 …

[HTML][HTML] Tibetan medicine duoxuekang capsule ameliorates high-altitude polycythemia accompanied by brain injury

K Chen, N Li, F Fan, ZJ Geng, K Zhao… - Frontiers in …, 2021 - frontiersin.org
high altitude of 5000 m in an animal hypobaric and hypoxic … protein concentration was
measured by a BCA protein quantitativeAfter administration of DXK, these pathological changes

[HTML][HTML] Molecular mechanisms of high-altitude acclimatization

RT Mallet, J Burtscher, V Pialoux, Q Pasha… - International journal of …, 2023 - mdpi.com
… effects of acute high-altitude/hypoxia exposure or the developing … Quantitative proteomics
and biochemical assays were … an altitude camp require measuring the changes in hemoglobin …

Hypoxia and low temperature upregulate transferrin to induce hypercoagulability at high altitude

M Li, X Tang, Z Liao, C Shen, R Cheng… - … , The Journal of the …, 2022 - ashpublications.org
… at high altitude, although their concentrations did not changehypoxia and low-temperature
treatment was determined by … -stained coronal brain sections (H) and quantitative analysis …