Src regulation of Cx43 phosphorylation and gap junction turnover
JL Solan, PD Lampe - Biomolecules, 2020 - mdpi.com
… We observed high levels of MAPK phosphorylation on S279/… that Src mediated downregulation
of gap junction size and number … Indeed, we saw the biggest changes in phosphorylation …
of gap junction size and number … Indeed, we saw the biggest changes in phosphorylation …
Ceramide/protein phosphatase 2A axis is engaged in gap junction impairment elicited by PCB153 in liver stem-like progenitor cells
… by phosphorylation [50]. Thus, we further studied the potential role of PP2A in mediating
its … (C8-Cer, 8 µM), a cell permeable synthetic analog of Cer. Our results indicate that C8-Cer …
its … (C8-Cer, 8 µM), a cell permeable synthetic analog of Cer. Our results indicate that C8-Cer …
[HTML][HTML] Phosphorylation-dependent allosteric regulation of Cx43 gap junction inhibitor potency
R Mickus, V Raškevičius, I Sarapinienė… - Biomedicine & …, 2024 - Elsevier
… single channel conductance or permeability. Mostly, phosphorylation-dependent changes
in GJ … -activated protein kinase (MAPK)-mediated phosphorylation of S255, S279, and S282; …
in GJ … -activated protein kinase (MAPK)-mediated phosphorylation of S255, S279, and S282; …
Endocrine-disrupting chemicals affect Sertoli TM4 cell functionality through dysregulation of gap junctional intercellular communication in vitro
… After the exposure, the cells were washed with PBS and gap junction permeable tracer …
the changes in Cx43 phosphorylation can translate into alterations in gap junction organization, …
the changes in Cx43 phosphorylation can translate into alterations in gap junction organization, …
Remodeling of cardiac gap junctional cell–cell coupling
S Dhein, A Salameh - Cells, 2021 - mdpi.com
… on the pure number of gap junction channels but also on … to depend on the phosphorylation
/ de-phosphorylation status of … that provokes these changes in gap junction location. However…
/ de-phosphorylation status of … that provokes these changes in gap junction location. However…
Gap Junctional Intercellular Communication: Role of Cx43 Phosphorylation by Tyrosine Kinases
I Basu - 2023 - digitalcommons.unmc.edu
… the gap junction including assembly, stability, internalization, turnover, channel permeability
… in Cx43 phosphorylation-mediated regulation of gap junctional intercellular communication. …
… in Cx43 phosphorylation-mediated regulation of gap junctional intercellular communication. …
Serine phosphorylation of the RhoGEF Trio stabilizes endothelial cell-cell junctions
AE Daniel, WJ van der Meer, L Wester… - Small …, 2023 - Taylor & Francis
… stability upon permeability-inducing reagents such as … tyrosine phosphorylation of Trio
regulates netrin-1/DCC-mediated cortical … that showed changes in their phosphorylation pattern in …
regulates netrin-1/DCC-mediated cortical … that showed changes in their phosphorylation pattern in …
Endocrine-disrupting chemicals rapidly affect intercellular signaling in Leydig cells
A Yawer, E Sychrová, P Labohá, J Raška… - Toxicology and Applied …, 2020 - Elsevier
… After the exposure, a gap junction permeable tracer lucifer … -specific phosphorylation of Cx43,
we examined the phosphorylation … MAPK- and PKC-mediated phosphorylation of Cx43 on …
we examined the phosphorylation … MAPK- and PKC-mediated phosphorylation of Cx43 on …
CDK5 activity in retinal pigment epithelium contributes to gap junction dynamics during phagocytosis
J Fadjukov, S Wienbar, N Milićević, S Hakanen… - bioRxiv, 2023 - biorxiv.org
… the localization of Cx43 connexons changes during the process. … Our results reveal that the
change in gap junction … observed gap junction dynamics are regulated by phosphorylation …
change in gap junction … observed gap junction dynamics are regulated by phosphorylation …
[PDF][PDF] Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatic cells and mouse liver
LJ Nelson - academia.edu
… This study also found histopathophysiological changes, at only 90 … , whilst PKC–mediated
phosphorylation of focal adhesion proteins … Increased intestinal permeability and tight junction …
phosphorylation of focal adhesion proteins … Increased intestinal permeability and tight junction …