ACE2 and gut amino acid transport
SMR Camargo, RN Vuille-dit-Bille, CF Meier… - Clinical …, 2020 - portlandpress.com
… Single cell RNA sequencing data analysis of colonic … amino acid transporter expression
in the small intestine of Ace2 knockout mice, we observed that these animals lack intestinal B …
in the small intestine of Ace2 knockout mice, we observed that these animals lack intestinal B …
SLC6A14, a Na+/Cl−-coupled amino acid transporter, functions as a tumor promoter in colon and is a target for Wnt signaling
MOF Sikder, S Sivaprakasam, TP Brown… - Biochemical …, 2020 - portlandpress.com
… (B) Western blot analysis of SLC6A14 protein levels in CCD841 cells and in … in both groups
were injected subcutaneously with the mouse colon cancer cell line MC-38 (106 cells/mouse)…
were injected subcutaneously with the mouse colon cancer cell line MC-38 (106 cells/mouse)…
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer
AK Najumudeen, F Ceteci, SK Fey, G Hamm… - Nature …, 2021 - nature.com
… Using mouse models, we demonstrate that the Kras-mutant cells specifically upregulate the
amino acid transporter … In agreement with Slc7a5 induction in APC KRAS mice, this analysis …
amino acid transporter … In agreement with Slc7a5 induction in APC KRAS mice, this analysis …
[HTML][HTML] Amino acid homeostasis in mammalian cells with a focus on amino acid transport
S Bröer, G Gauthier-Coles - The Journal of nutrition, 2022 - Elsevier
… in the colon (10, 11). … amino acid transporters (Figure 2) are expressed on the apical
membrane for the absorption of neutral amino acids (B 0 AT1, broad neutral amino acid transporter 1…
membrane for the absorption of neutral amino acids (B 0 AT1, broad neutral amino acid transporter 1…
Changes to gut amino acid transporters and microbiome associated with increased E/I ratio in Chd8+/− mouse model of ASD-like behavior
Y Yu, B Zhang, P Ji, Z Zuo, Y Huang, N Wang… - Nature …, 2022 - nature.com
… from colon of 12-week-old mice (pg/mg protein). n = 11 and 10 … To explore the effect of B.
uniformis on the intestinal … , we performed RNA-seq analysis of small intestinal cells. For the …
uniformis on the intestinal … , we performed RNA-seq analysis of small intestinal cells. For the …
Amino acids in intestinal physiology and health
M Beaumont, F Blachier - … in Nutrition and Health: Amino acids in systems …, 2020 - Springer
… ); while for the colonocytes, the amino acid supply is believed to be … controversial as some
amino acid transporters have been … Metabolism of essential amino acids in colonic epithelial …
amino acid transporters have been … Metabolism of essential amino acids in colonic epithelial …
[HTML][HTML] Amino acid metabolism, transport and signalling in the liver revisited
… of hepatic amino acid transport. In Table 1 the expression of … More detailed analysis of
mRNA sequencing data obtained … levels in liver tissue were normal in TAT1 knock-out mice on …
mRNA sequencing data obtained … levels in liver tissue were normal in TAT1 knock-out mice on …
L-type amino acid transporter 1 is associated with chemoresistance in breast cancer via the promotion of amino acid metabolism
M Sato, N Harada-Shoji, T Toyohara, T Soga, M Itoh… - Scientific reports, 2021 - nature.com
… are amino acid levels uptake via LAT1 with control set to 1 (B)… We performed a metabolomic
analysis of LAT1-knockout and … We used cells stably expressing hLAT1 (S2-LAT1), a mouse …
analysis of LAT1-knockout and … We used cells stably expressing hLAT1 (S2-LAT1), a mouse …
Amino Acid Transporter SLC6A14 (ATB0,+) – A Target in Combined Anti-cancer Therapy
KA Nałęcz - Frontiers in cell and developmental biology, 2020 - frontiersin.org
… transporter called system B 0,+ (amino acid transporter ATB 0… surgical specimen of patients
with colorectal cancer, as well as … pancreatic cancer cells characterized by various SLC6A14 …
with colorectal cancer, as well as … pancreatic cancer cells characterized by various SLC6A14 …
Amino acid transporters and exchangers from the SLC1A family: structure, mechanism and roles in physiology and cancer
… extensive structural characterisation. Glt Ph shares 30–40% … b Side-view of a monomer
with HP2 shown in red, aspartate … in colon cancer, which the authors propose fulfils a similar …
with HP2 shown in red, aspartate … in colon cancer, which the authors propose fulfils a similar …