[HTML][HTML] The Shigella type III secretion system: an overview from top to bottom

M Muthuramalingam, SK Whittier, WL Picking… - Microorganisms, 2021 - mdpi.com
… a needle-associated tip complex with associated translocon that is … to three bacterial
genera—Shigella flexneri, Salmonella … The in situ translocon has been difficult to fully characterize

Type three secretion system in Salmonella Typhimurium: the key to infection

AMP Dos Santos, RG Ferrari, CA Conte-Junior - Genes & genomics, 2020 - Springer
… T3SS structure comprises a translocon, formed by the translocators SctB and SctE and the
tip … Corroborating with this hypothesis, a cryo-EM analysis of Salmonella Typhimurium T3SS …

The tip complex: From host cell sensing to translocon formation

WD Picking, ML Barta - Bacterial type III protein secretion systems, 2020 - Springer
… In this review, all three of these type III secretion systems are … T3SS arguably represent the
best-characterized T3SS with … current level of understanding of type III secretion in Shigella. …

Composition and Biophysical Properties of the Sorting Platform Pods in the Shigella Type III Secretion System

S Tachiyama, R Skaar, Y Chang, BL Carroll… - Frontiers in Cellular …, 2021 - frontiersin.org
… The needle tip complex is exposed on the bacterial surface … was used to measure of translocon
formation. Spa33 FL did … Based on two-hybrid analysis, we found that MxiK was able to …

[PDF][PDF] The Shigella Type III Secretion System: An Overview from Top to Bottom. Microorganisms 2021, 9, 451

…, SK Whittier, WL Picking, WD Picking III - 2021 - pdfs.semanticscholar.org
… The in situ translocon has been difficult to fully characterize … to the Shigella type III secretion
system tip complex protein IpaD… type III secretion translocon. Protein Sci. 2013, 22, 614–627. …

The T3SS of Shigella: Expression, Structure, Function, and Role in Vacuole Escape

W Bajunaid, N Haidar-Ahmad, AH Kottarampatel… - Microorganisms, 2020 - mdpi.com
characterized by the harboring of a large plasmid that encodes most virulence genes, including
a type III secretion system (… the tip complex to the translocon (Figure 1b). Interestingly, the …

Transmembrane substrates of type three secretion system injectisomes

C Godlee, DW Holden - Microbiology, 2023 - microbiologyresearch.org
… The translocon fragments used for characterization of the … , the major translocon proteins
of Shigella and Salmonella SPI-1 … The type III secretion system needle tip complex mediates …

Identification of Novel Type III Secretion System Determinants in Shigella flexneri

A Peschel - 2023 - tobias-lib.ub.uni-tuebingen.de
… The filamentous type III secretion translocon of … analysis of chaperone dependence in the
process of type III effector … protein complex at the tip of the needle, the translocon, forms a pore …

Assembly and post-assembly turnover and dynamics in the type III secretion system

A Diepold - Bacterial Type III Protein Secretion Systems, 2020 - Springer
… -step translocation mechanism can also lead to translocation. … this hypothesis, the recent
structural characterization of the P. … , the Yersinia/Salmonella/Shigella-specific names are listed. …

Cryo-EM structure of the Shigella type III needle complex

M Lunelli, A Kamprad, J Bürger, T Mielke… - PLoS …, 2020 - journals.plos.org
… molecular mechanisms of effector translocation. Here, we … [4], which employ a Type III
Secretion System (T3SS), also … is supported by our analysis of the Shigella needle complex, …