Analysis of assembly and function of bacterial type III secretion systems

N Singh - 2023 - tobias-lib.ub.uni-tuebingen.de
… and SctK in Salmonella enterica type III secretion system ..........… translocon get effectively
secreted in the absence of the tip … in Shigella [63], which agrees with the extraordinary level of …

Conserved salt bridges facilitate assembly of the helical core export apparatus of a Salmonella enterica Type III secretion system

N Singh, T Kronenberger, A Eipper, F Weichel… - Journal of Molecular …, 2021 - Elsevier
analysis of these residues in the T3SS of Salmonella … All of its components are indispensable
for the translocation … SctR 5 S 4 T 1 core complex based on the Shigella flexneri Sct R 5 S 4 …

[HTML][HTML] Recent structural advances towards understanding of the bacterial type III secretion injectisome

J Jenkins, LJ Worrall, NCJ Strynadka - Trends in Biochemical Sciences, 2022 - cell.com
… New structural insights into the bacterial type III secretion system. … The distal end of the
filament consists of the tip (SctA) and the translocon pore (SctB and SctE) which form a channel …

Novel Noncompetitive Type Three Secretion System ATPase Inhibitors Shut Down Shigella Effector Secretion

HB Case, DS Mattock, BR Miller III, NE Dickenson - Biochemistry, 2020 - ACS Publications
… protein tip assembly that … characterized in this study against the T3SS ATPases EscN from
enteropathogenic Escherichia coli (EPEC) and the flagellar T3SS ATPase FliI from Salmonella

Insights into the Bacterial Type III Secretion System

H Das, C Goswami, L Rose, SM Gogoi… - … Journal of Bio …, 2022 - ojs.pphouse.org
… Phylogenetic analysis came up with evidence that bacterial Type III … the translocon and
tip component to be close to the host cell membrane. Even the swarming ability of Shigella can …

Virulence-associated type III secretion systems in Gram-negative bacteria

SV Pais, E Kim, S Wagner - Microbiology, 2023 - microbiologyresearch.org
… Structure and components of a type III secretion system (T3SS… Cryo-ET analysis revealed
that the formation of the translocon … needle tip was shown to function as a guide for translocon

Dynamic relocalization of cytosolic type III secretion system components prevents premature protein secretion at low external pH

S Wimmi, A Balinovic, H Jeckel, L Selinger… - Nature …, 2021 - nature.com
… genera, including Salmonella, Shigella, pathogenic Escherichia, … avoid protein translocation
into non-host cells, secretion itself … the outlines of the pH 7 analysis. c Spatial stability of SctV-…

Characterization of type III secretion system-dependent protein secretion in Y. enterocolitica

BA Milne-Davies - 2021 - archiv.ub.uni-marburg.de
Salmonella, Shigella and Pseudomonas utilize their T3SS to manipulate the host immune
system … able to export the tip and translocon, which allows translocation of effector proteins. …

icaR and icaT are Ancient Chromosome Genes Encoding Substrates of the Type III Secretion Apparatus in Shigella flexneri

N Silué, FX Campbell-Valois - Msphere, 2022 - Am Soc Microbiol
… some of their characteristics suggest they are fossil genes. … The type III secretion system
(T3SS) of Shigella is essential to … translocators, which form the translocon that allows the transfer …

A Salmonella type III effector, PipA, works in a different manner than the PipA family effectors GogA and GtgA

M Takemura, T Haneda, H Idei, T Miki, N Okada - PLoS One, 2021 - journals.plos.org
… Typhimurium has two independent type III secretion systems (T3SSs), … The translocation of
these effectors into the host cells … A comprehensive analysis of the Salmonella type III effectors …