[HTML][HTML] A new Neu—a syngeneic model of spontaneously metastatic HER2-positive breast cancer
AG Baugh, E Gonzalez, VH Narumi, J Kreger… - Clinical & Experimental …, 2024 - Springer
… , we characterize a novel syngeneic murine breast tumor cell … in pro-metastatic phenotypes
by comparing gene expression … upregulate the expression of Mena INV , a spliced isoform of …
by comparing gene expression … upregulate the expression of Mena INV , a spliced isoform of …
[HTML][HTML] Mimicking the breast metastatic microenvironment: characterization of a novel syngeneic model of HER2+ breast cancer
AG Baugh, E Gonzalez, VH Narumi, J Kreger, Y Liu… - bioRxiv, 2024 - ncbi.nlm.nih.gov
… the differences in pro-metastatic phenotypes by comparing gene expression profiles between
NT2.… journey tend to upregulate the expression of Mena INV , a spliced isoform of the actin-…
NT2.… journey tend to upregulate the expression of Mena INV , a spliced isoform of the actin-…
Scaffold stiffness influences breast cancer cell invasion via EGFR-linked Mena upregulation and matrix remodeling
… Analysis of fibronectin isoforms demonstrated that EDA-fibronectin promoted invasion …
expression of MENA-INV, a splice variant that imparts a more invasive phenotype in breast cancer …
expression of MENA-INV, a splice variant that imparts a more invasive phenotype in breast cancer …
[HTML][HTML] Propensity for early metastatic spread in breast cancer: Role of tumor vascularization features and tumor immune infiltrate
MR D'Andrea, V Cereda, L Coppola, G Giordano… - Cancers, 2021 - mdpi.com
… of breast tumor environment characteristics (tumor … derived from the high expression of Mena
isoforms, and facilitating … VEGF and Tie2, may have a pro-metastatic role [109]. Interestingly…
isoforms, and facilitating … VEGF and Tie2, may have a pro-metastatic role [109]. Interestingly…
[HTML][HTML] Cooperative NF-κB and Notch1 signaling promotes macrophage-mediated MenaINV expression in breast cancer
… These changes are characterized by macrophage recruitment, increased TMEM doorway …
expression of MenaINV, a pro-metastatic isoform of Mena, in breast cancer cells through …
expression of MenaINV, a pro-metastatic isoform of Mena, in breast cancer cells through …
[HTML][HTML] A novel invadopodia-specific marker for invasive and pro-metastatic cancer stem cells
SS Huang, WY Liao, CC Hsu, TS Chan, TY Liao… - Frontiers in …, 2021 - frontiersin.org
… regulator (MENA; MENA INV ), has been shown to inhibit tumor … of cancers, we repeated the
FACS analysis in primary tumor-… Interestingly, emerging data in breast cancer suggests that …
FACS analysis in primary tumor-… Interestingly, emerging data in breast cancer suggests that …
[HTML][HTML] Combining TMEM Doorway Score and MenaCalc Score Improves the Prediction of Distant Recurrence Risk in HR+/HER2− Breast Cancer Patients
… Of the 130 patients, 86 cases were suitable for analysis in … a Mena INV-Hi and Mena11a
Low isoform expression pattern… amounts of pro-metastatic and anti-metastatic Mena isoforms. …
Low isoform expression pattern… amounts of pro-metastatic and anti-metastatic Mena isoforms. …
[HTML][HTML] Are we ready for migrastatics?
J Solomon, M Raškova, D Rösel, J Brábek, H Gil-Henn - Cells, 2021 - mdpi.com
… in colorectal cancer patients and breast cancer patients. … showed a decreased capacity to
migrate, a reduced pro-metastatic … (MENA) isoform expression patterns (Mena Calc and Mena …
migrate, a reduced pro-metastatic … (MENA) isoform expression patterns (Mena Calc and Mena …
[PDF][PDF] High FOXA1 levels induce ER transcriptional reprogramming, a pro-metastatic secretome, and metastasis in endocrine-resistant breast cancer
… Next, using the binding and expression target analysis (BETA) algorithm,33 we identified
471 upregulated (UP) and 311 downregulated (DN) genes in +Dox vs. ÀDox cells (Table S2), …
471 upregulated (UP) and 311 downregulated (DN) genes in +Dox vs. ÀDox cells (Table S2), …
Significant roles of ITGB3 in the tumour microenvironment: EMT driver in hypoxic conditions and central axis in intercellular communication
P Fuentes Varela - 2020 - ddd.uab.cat
… conditions and is important for breast cancer survival and migration ..… Analysis of
transcriptionally downregulated genes under … Analysis of transcriptionally deregulated genes …
transcriptionally downregulated genes under … Analysis of transcriptionally deregulated genes …