… (5R-hepcidin). … hepcidin we demonstrated that hepcidin can compete for Cd(II) ions with
metallothionein-2, a cellular cadmium target. This study enabled us to conclude that hepcidin …

… Hepcidin is an iron regulatory hormone that does not bind iron directly. Instead, its mature
25… The Cu(II)-hepcidin complex was previously studied, but due to poor solubility and difficult …

… and mechanistic properties of ill-characterized metalloproteins at … hepcidin without evidence
of transition metal binding [64]. Similarly, production of C-terminal histidine-tagged hepcidin …

… During infection, the small peptide hormone hepcidin is secreted from the liver (12-14). It …
We next tested whether calprotectin association with Bb required transition metal binding sites …

… hepcidin (gene name: HAMP) which functions by preventing cellular iron export through
ferroportin. Consequently, sustained elevated hepcidin … We then explored hepcidin’s regulatory …

… NMC–Cu 2+ complexes were further characterized by pH titration. The stoichiometries
and overall stability constants (log β pqr ) thus determined, which are shown in Table 2, were …

… Because the Heffern lab has characterized the Cu-binding properties of C-peptide, we …
function of bioactive peptides at a molecular level such as insulin, oxytocin, and hepcidin.…

… necessary to explore the metal binding characteristics of two metal transporters from … the
hormone hepcidin (56). Iron overload can be caused by mutations affecting hepcidin production, …

Hepcidin 25 (hep 25) is a cysteine-rich 25-amino acid antimicrobial peptide containing the
amino-terminal Cu(II)/Ni(II)-binding (ATCUN) motif. Upon metal binding, the ATCUN motif is …

… (Cp), and hephaestin are coordinated by hepcidin (Hep) to ensure efficient Fe acquisition …
young women was described as being characterized by lethargy, decreased work capacity, …