… and Chemical Synthesis of Cm39 (α-KTx 4.8): A Scorpion Toxin That Inhibits Voltage-Gated K+ Channel KV1.2 and Small- and Intermediate-Conductance Ca2+-Activated K+ Channels K …
…, J Beltrán-Vidal, FZ Zamudio, K Shakeel… - Toxins, 2023 - mdpi.com
… experiments to reveal novel interactions with the vestibule of toxin-sensitive channels. … ,
ε-KTx, κ-KTx and λ-KTx [23]. α-KTxs are the most abundant toxins found in scorpion venom and …
ε-KTx, κ-KTx and λ-KTx [23]. α-KTxs are the most abundant toxins found in scorpion venom and …
… three-dimensional structure of the cationic peptide Stigmurin from Tityus stigmurus scorpion venom: In vitro antioxidant and in vivo antibacterial and healing activity
A Daniele-Silva, SCS Rodrigues, ECG Dos Santos… - Peptides, 2021 - Elsevier
… structural information, allied with the multifunctional activity of Stigmurin, makes it an attractive
candidate for the design of novel … the structure-activity relationship of this bioactive peptide. …
candidate for the design of novel … the structure-activity relationship of this bioactive peptide. …
Antimicrobial peptide analogs from scorpions: Modifications and structure-activity
B Amorim-Carmo, AMS Parente, ES Souza… - Frontiers in Molecular …, 2022 - frontiersin.org
… Thus, this review aims to address the AMPs found in scorpion venom and the most … activity
and modulate their toxicity to human cells, in addition to the possible application of scorpion …
and modulate their toxicity to human cells, in addition to the possible application of scorpion …
Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom
K Luna-Ramirez, A Csoti, JR McArthur… - Biochemical …, 2020 - Elsevier
… the basis for scorpion toxin classification, with six KTx subfamilies (α, β, γ, δ, κ, and λ) …
GFP-positive transfected cells were identified using a Nikon Eclipse TS-100 fluorescence …
GFP-positive transfected cells were identified using a Nikon Eclipse TS-100 fluorescence …
Tityus serrulatus scorpion venom as a potential drug source for Chagas' disease: Trypanocidal and immunomodulatory activity
PM de Oliveira Pimentel, DRR de Assis… - Clinical …, 2021 - Elsevier
… The venom of the Brazilian yellow scorpion Tityus serrulatus (TsV) has been studied in …
structure-activity relationship studies showed that a tripeptide (KPP) was able to mimic the activity …
structure-activity relationship studies showed that a tripeptide (KPP) was able to mimic the activity …
Functional Characterization of a New Degradation Peptide BmTX4-P1 from Traditional Chinese Scorpion Medicinal Material
C Qin, X Yang, Y Zhang, G Deng, X Huang, Z Zuo… - Toxins, 2023 - mdpi.com
… the venom gland of traditional Chinese scorpion medicinal material. Considering the effective
medicinal value of the thermally processed scorpion venom … -P1 by chemical synthesis. …
medicinal value of the thermally processed scorpion venom … -P1 by chemical synthesis. …
[PDF][PDF] Scorpion Toxin-potassium Channel Interaction Law and its Applications
Z Zuo, Z Chen, Z Cao, W Li, Y Wu - neurotoxins, 2021 - researchgate.net
… amino acids in toxin κ-PVIIA, which make κ-PVIIA a typical polar molecule (Figs. 7A). Similar
to … Chemical synthesis and structure-activity relationships of Ts kappa, a novel scorpion toxin …
to … Chemical synthesis and structure-activity relationships of Ts kappa, a novel scorpion toxin …
[HTML][HTML] Exploring the potential of Brazilian Amazonian scorpion venoms: A comprehensive review of research from 2001 to 2021
JR da Cruz, P Bulet, CM de Moraes - Toxicon: X, 2023 - Elsevier
… beneficial properties of scorpion venom toxins and how they … an opportunity to uncover
novel bioactive compounds that … , while also developing novel technologies and therapies that …
novel bioactive compounds that … , while also developing novel technologies and therapies that …
Spider-Venom Peptides: Structure, Bioactivity, Strategy, and Research Applications
R Guo, G Guo, A Wang, G Xu, R Lai, H Jin - Molecules, 2023 - mdpi.com
… compete with the classical scorpion κ toxin AaH II for … novel tool for investigating sodium
channel voltage sensors and holds the potential to elucidate the relationships between structure …
channel voltage sensors and holds the potential to elucidate the relationships between structure …
Structural and functional studies of LaIT2, an antimicrobial and insecticidal peptide from Liocheles australasiae
M Tamura, C Tatsushiro, EH Morita, S Ohki - Toxicon, 2022 - Elsevier
… a peptide toxin isolated from the venom of the Yaeyama scorpion, … Design and synthesis of
novel antimicrobial peptides on the … defensin protein, and structure-activity relationship study …
novel antimicrobial peptides on the … defensin protein, and structure-activity relationship study …