[HTML][HTML] Combined chemotherapy with cyclooxygenase-2 (COX-2) inhibitors in treating human cancers: Recent advancement

S Li, M Jiang, L Wang, S Yu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
… therapy or chemoprevention [2]. Furthermore, … the addition of celecoxib to CapeOX therapy
for colon cancer was unable … to administer doxorubicin and celecoxib for drug-resistant breast …

[HTML][HTML] Non-steroidal anti-inflammatory drugs in colorectal cancer chemoprevention

J Maniewska, D Jeżewska - Cancers, 2021 - mdpi.com
… of colorectal polyps, mostly by cyclooxygenase-2 inhibition. … and celecoxib) in chemoprevention
of colorectal cancer was … a terminal to a chronic one that can be taken under control. …

Gut-restricted selective cyclooxygenase-2 (COX-2) inhibitors for chemoprevention of colorectal cancer

Z Zhang, A Ghosh, PJ Connolly, P King… - Journal of Medicinal …, 2021 - ACS Publications
… , was to identify a colon-targeted, orally administered, COX-2-selective inhibitor that would
suppress … superior in vivo chemopreventive effects over celecoxib at the highest doses tested. …

Targeting cyclooxygenase-2 for chemoprevention of inflammation-associated intestinal carcinogenesis: An update

KS Chun, EH Kim, DH Kim, NY Song, W Kim… - Biochemical …, 2024 - Elsevier
colorectal cancer [75]. Oral administration of PGE 2 enhanced the colorectal and small …
Thus, treatment of Apc Min+/- mice with celecoxib not only reduced intestinal PGE 2 levels, …

[HTML][HTML] The role of cyclooxygenase-2 in colorectal cancer

J Sheng, H Sun, FB Yu, B Li, Y Zhang… - International journal of …, 2020 - ncbi.nlm.nih.gov
… mechanism of colorectal cancer have not been fully understood. For example, cyclooxygenase-2
(… Combination of aromatase inhibitors with celecoxib is better for patients suffering from …

Celecoxib, a selective cyclooxygenase-2 inhibitor, aggravates radiation-induced intestinal damage in mice

S Lee, JM Chun, JH Lee, YS Seo, JH Park… - Journal of Biomedical …, 2021 - jbtr.or.kr
inhibitors reportedly inhibit tumor growth [6]. Accordingly, the usefulness of COX-2 inhibitors
for chemoprevention in colorectal cancer … tract after celecoxib was administered to irradiated …

[HTML][HTML] Colorectal carcinoma, cyclooxygenases, and Cox inhibitors

V Ganduri, K Rajasekaran, S Duraiyarasan… - Cureus, 2022 - ncbi.nlm.nih.gov
chemoprevention on colon cancer was conducted by following over 600,000 individuals for
colon cancer … patients who might benefit from celecoxib chemoprevention since it is no more …

Celecoxib for stage III colon cancer

DJ Kerr, S Chamberlain, RS Kerr - JAMA, 2021 - jamanetwork.com
cyclooxygenase-2 (COX-2) inhibitors to prevention of colorectal adenomas and colorectal
cancer… the selective COX-2 inhibitor celecoxib vs placebo, administered for 3 years, as an …

[HTML][HTML] Protective Effects of Long-Term Usage of Cyclo-Oxygenase-2 Inhibitors on Colorectal Cancer in Genetically Predisposed Individuals and Their Overall Effect …

SH Narayana, U Mushtaq, BS Ameen, C Nie, D Nechi… - Cureus, 2023 - ncbi.nlm.nih.gov
… of aspirin in chemoprevention of colorectal cancer. 0 Aspirin … [22] Narrative Review Role of
celecoxib in colorectal cancer. … , its possible toxicity needs to be taken into account. However, …

[HTML][HTML] Effects of genetic and pharmacologic inhibition of COX-2 on colitis-associated carcinogenesis in mice

JS Lee, HS Kim, KB Hahm, YJ Surh - Journal of cancer prevention, 2020 - ncbi.nlm.nih.gov
… and this was inhibited by celecoxib administration. Likewise, … the chemopreventive effects
of pharmacological inhibition and … days failed to induce colon tumor formation. However, the …