Chemopreventive activity of bioactive fungal fractions isolated from milk-supplemented cultures of Cerrena unicolor and Pycnoporus sanguineus on colon cancer …
M Pięt, A Zając, R Paduch, M Jaszek, M Frant… - 3 Biotech, 2021 - Springer
The biochemical properties and anti-tumorigenic activity of Cerrena unicolor (CU) and
Pycnoporus sanguineus (PS) towards colon cancer cells and the effect of supplementation
of the fungal culture medium with cow milk on these activities were examined. CU1-II and
PS4-II exhibited anticancer properties through various mechanisms. The extracts at the 200
µg/mL concentration significantly decreased the viability of HT-29 and SW948 cells. They
also exhibited pro-apoptotic properties towards the cancer cell lines (HT-29, LS 180, and …
Pycnoporus sanguineus (PS) towards colon cancer cells and the effect of supplementation
of the fungal culture medium with cow milk on these activities were examined. CU1-II and
PS4-II exhibited anticancer properties through various mechanisms. The extracts at the 200
µg/mL concentration significantly decreased the viability of HT-29 and SW948 cells. They
also exhibited pro-apoptotic properties towards the cancer cell lines (HT-29, LS 180, and …
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